1-Aminomethyl-5-methoxyindane

Chemical compound
  • none
Legal statusLegal status
  • In general: uncontrolled
Identifiers
  • (5-Methoxy-2,3-dihydro-1H-inden-1-yl)methanamine
CAS Number
  • 1415750-28-5 ☒N
PubChem CID
  • 45091234
ChemSpider
  • 24205063 checkY
UNII
  • 585V6BDH9X
Chemical and physical dataFormulaC11H15NOMolar mass177.247 g·mol−13D model (JSmol)
  • Interactive image
  • NCC1CCc2c1ccc(OC)c2
InChI
  • InChI=1S/C11H15NO/c1-13-10-4-5-11-8(6-10)2-3-9(11)7-12/h4-6,9H,2-3,7,12H2,1H3 checkY
  • Key:WPBKCMLYKMDWRD-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

1-Aminomethyl-5-methoxyindane (AMMI), is a drug developed by a team led by David E. Nichols at Purdue University, which acts as a selective serotonin releasing agent (SSRA) and binds to the serotonin transporter with similar affinity to DFMDA.[1][2]

See also

  • 2CB-Ind

References

  1. ^ Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL (February 2004). "Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters". The Journal of Pharmacology and Experimental Therapeutics. 308 (2): 679–87. doi:10.1124/jpet.103.057836. PMID 14593087. S2CID 6439942.
  2. ^ Walline CC, Nichols DE, Carroll FI, Barker EL (June 2008). "Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition". The Journal of Pharmacology and Experimental Therapeutics. 325 (3): 791–800. doi:10.1124/jpet.108.136200. PMC 2637348. PMID 18354055.
  • v
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Empathogens/entactogens
Phenylalkyl-
amines
(other than
cathinones)
Cyclized phenyl-
alkylamines
CathinonesTryptaminesChemical classes
  • v
  • t
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DRAsTooltip Dopamine releasing agents
NRAsTooltip Norepinephrine releasing agents
SRAsTooltip Serotonin releasing agents
Others
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins