4-Bromomethcathinone
Psychoactive drug and research chemical
- 1-(4-bromophenyl)-2-(methylamino)propan-1-one
- 486459-03-4 Y
- 10421832
- 8597261 N
- 9GU9FVS6HH
- DTXSID401014169
- Interactive image
- CC(C(=O)C1=CC=C(C=C1)Br)NC
InChI
- InChI=1S/C10H12BrNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3 N
- Key:OOJXMFNDUXHDOV-UHFFFAOYSA-N N
4-Bromomethcathinone (4-BMC, Brephedrone) is a psychoactive drug and research chemical of the phenethylamine, amphetamine, and cathinone chemical classes. It acts as a serotonin and norepinephrine reuptake inhibitor,[1][2] but acts more like an antidepressant than a stimulant.[3] Some 4-halogenated cathinones seem to share the selective serotonergic neurotoxicity of their corresponding amphetamine analogues.[4]
Legal status
As of October 2015, 4-BMC is a controlled substance in China.[5] 4-Bromomethcathinone is considered a Schedule 1 substance in Virginia.[6]
See also
References
- ^ Foley KF, Cozzi NV (1999). "Bromine substitution at the ring 3- or 4-position of methcathinone enhances potency at serotonin uptake transporters". Society for Neuroscience Abstracts. 25 (1–2): 1701. 678.17. Archived from the original on 2013-09-07. Retrieved 2013-07-28.
- ^ Foley KF, Cozzi NV (June 2002). "Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N-ethylmaleimide and protection by substrate analogs". Naunyn-Schmiedeberg's Archives of Pharmacology. 365 (6): 457–461. doi:10.1007/s00210-002-0532-3. PMID 12070759. S2CID 3244808.
- ^ Foley KF, Cozzi NV (2003). "Novel aminopropiophenones as potential antidepressants" (PDF). Drug Development Research. 60 (4): 252–260. doi:10.1002/ddr.10297. S2CID 84128787. Archived from the original (PDF) on 2016-03-06. Retrieved 2015-09-09.
- ^ Wojcieszak J, Kuczyńska K, Zawilska JB (August 2020). "Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles". Neurotoxicity Research. 38 (2): 536–551. doi:10.1007/s12640-020-00227-8. PMC 7334283. PMID 32506339.
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
- ^ "18VAC110-20-322. Placement of Chemicals in Schedule I." Commonwealth of Virginia. 2 December 2015. Retrieved 11 March 2016.
- v
- t
- e
amines
(other than
cathinones)
- Unfused benzene ring: 3-CMA
- 4-CAB
- 4-FA
- 4-MA
- 4-MMA
- 4-FMA
- 4-MTA
- 4,4'-DMAR
- Ariadne
- Metaescaline
- MMA
- PMA
- PMEA
- PMMA
- mMMA
Benzodioxine: EDMA
Benzodioxoles: Phenethylamine: { Lophophine } - Amphetamines: { 2-Methyl-MDA
- 2,3-MDA
- 3,4-MDA (tenamfetamine)
- 5-Methyl-MDA
- 6-Methyl-MDA
- DFMDA
- DMMDA
- DMMDA-2
- EIDA
- Lys-MDA
- MDEA
- MDMA (midomafetamine)
- MDMOH
- MDOH
- MMDA
- MMDA-2
- MMDMA
- N-t-BOC-MDMA }
- 1-Phenylbutan-2-amines: { BDB
- EBDB
- MBDB }
- Phentermines: { MDMP
- MDPH }
Benzofurans, dihydrobenzofurans and benzothiophenes: 2-MAPB - 5-APB
- 5-APDB
- 5-EAPB
- 5-MAPB
- 5-MAPDB
- 5-MAPBT
- 5-MBPB
- 6-APB
- 6-APDB
- 6-EAPB
- 6-MAPB
- 6-MAPDB
- IBF5MAP
Indanes: 5-APDI - 5-MAPDI
Indoles: 5-IT - 6-API
Naphthalenes: Methamnetamine - Naphthylaminopropane
Tetralin: 6-APT
alkylamines
This psychoactive drug-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e