ARMC6

Protein-coding gene in the species Homo sapiens
ARMC6
Identifiers
AliasesARMC6, R30923_1, armadillo repeat containing 6
External IDsMGI: 1924063 HomoloGene: 14121 GeneCards: ARMC6
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ARMC6
Genomic location for ARMC6
Band19p13.11Start19,033,575 bp[1]
End19,060,311 bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for ARMC6
Genomic location for ARMC6
Band8|8 B3.3Start70,672,822 bp[2]
End70,687,116 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of liver

  • ganglionic eminence

  • right lobe of thyroid gland

  • prefrontal cortex

  • left lobe of thyroid gland

  • anterior pituitary

  • gastrocnemius muscle

  • right adrenal gland

  • Brodmann area 9

  • left adrenal gland
Top expressed in
  • barrel cortex

  • superior cervical ganglion

  • visual cortex

  • neural tube

  • superior frontal gyrus

  • spinal ganglia

  • morula

  • otic placode

  • yolk sac

  • trigeminal ganglion
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

93436

76813

Ensembl

ENSG00000105676

ENSMUSG00000002343

UniProt

Q6NXE6

Q8BNU0

RefSeq (mRNA)

NM_001199196
NM_033415

NM_133972

RefSeq (protein)

NP_001186125
NP_219483

NP_598733

Location (UCSC)Chr 19: 19.03 – 19.06 MbChr 8: 70.67 – 70.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The human gene ARMC6 encodes a protein called Armadillo repeat-containing protein 6.[5][6]

The function of this gene's protein product has not been determined. A related protein in mouse suggests that this protein has a conserved function.[6]

The protein is characterized by the presence of armadillo repeats in its amino acid sequence. Diseases associated with ARMC6 include pancreatic cancer, and pancreatitis.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105676 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002343 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ a b "Entrez Gene: ARMC6 armadillo repeat containing 6".

External links

Further reading

  • Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, et al. (2004). "The DNA sequence and biology of human chromosome 19" (PDF). Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
  • Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.


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