Acefylline
Chemical compound
- R03DA09 (WHO) (acefylline piperazine)
- (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid
- 652-37-9
N
- 69550
- 62754
Y
- M494UE2YEP
- ChEMBL70246 Y
- DTXSID6057796
- Interactive image
- O=C2N(c1ncn(c1C(=O)N2C)CC(=O)O)C
InChI
- InChI=1S/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15)Y
- Key:HCYFGRCYSCXKNQ-UHFFFAOYSA-NY
Acefylline (INN),[1] also known as 7-theophyllineacetic acid, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.[2]
A silanol–mannuronic acid conjugate of acefylline, acefylline methylsilanol mannuronate (INCI; trade name Xantalgosil C) is marketed as a lipolytic phosphodiesterase inhibitor. It is used as an ingredient in cosmeceuticals for the treatment of cellulite and as a skin conditioner.[3][4]
See also
References
- ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 21" (PDF). World Health Organization. Retrieved 29 December 2016.
- ^ Zuidema J (1978). "Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline". Thesis (doctoral)--Universiteit van Amsterdam. Archived from the original on 2016-12-30. Retrieved 2012-09-29.
{{cite journal}}: Cite journal requires|journal=(help) - ^ Biosil Technologies (2005). "Xantalgosil C® Datasheet" (PDF). Exsymol S.A.M. Retrieved 2022-01-20.
- ^ Winter, Ruth (2009-10-20). A Consumer's Dictionary of Cosmetic Ingredients (7th ed.). Harmony/Rodale. p. 42. ISBN 9780307459862.
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