Acrocinonide

Chemical compound
Acrocinonide
Clinical data
Other namesTriamcinolone acroleinide; Triamcinolone 16,17-2-propenal acetal; SD 2102-18; 9α-Fluoro-11β,21-dihydroxy-16α,17α-(2-propenylidenedioxy)pregna-1,4-dien-3,20-dione; 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acrolein
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a-dimethyl-8-vinyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
CAS Number
  • 28971-58-6
PubChem CID
  • 11743529
ChemSpider
  • 9918233
UNII
  • 67N58AU0IZ
ChEMBL
  • ChEMBL2105519
CompTox Dashboard (EPA)
  • DTXSID30183173 Edit this at Wikidata
Chemical and physical data
FormulaC24H29FO6
Molar mass432.488 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)C=C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O
InChI
  • InChI=1S/C24H29FO6/c1-4-20-30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,2)23(15,25)17(28)11-22(16,3)24(19,31-20)18(29)12-26/h4,7-9,15-17,19-20,26,28H,1,5-6,10-12H2,2-3H3/t15-,16-,17-,19+,20?,21-,22-,23-,24+/m0/s1
  • Key:JGSKXHVNDZFORI-DZPDXEKMSA-N

Acrocinonide (developmental code name SD 2102-18; also known as triamcinolone acroleinide) is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1228–. ISBN 978-1-4757-2085-3.


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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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