Agroclavine

Agroclavine
Names
IUPAC name
6,8-Dimethyl-8,9-didehydroergoline
Systematic IUPAC name
(6aR,10aR)-7,9-Dimethyl-4,6,6a,7,8,10a-hexahydroindolo[4,3-fg]quinoline
Other names
8,9-Didehydro-6,8-dimethylergoline
Identifiers
CAS Number
  • 548-42-5 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:2519 ☒N
ChEMBL
  • ChEMBL449081 checkY
ChemSpider
  • 66176 checkY
ECHA InfoCard 100.008.135 Edit this at Wikidata
PubChem CID
  • 73484
UNII
  • A8SW57GO7T checkY
CompTox Dashboard (EPA)
  • DTXSID10970144 Edit this at Wikidata
InChI
  • InChI=1S/C16H18N2/c1-10-6-13-12-4-3-5-14-16(12)11(8-17-14)7-15(13)18(2)9-10/h3-6,8,13,15,17H,7,9H2,1-2H3/t13-,15-/m1/s1 checkY
    Key: XJOOMMHNYOJWCZ-UKRRQHHQSA-N checkY
  • InChI=1S/C16H18N2/c1-10-6-13-12-4-3-5-14-16(12)11(8-17-14)7-15(13)18(2)9-10/h3-6,8,13,15,17H,7,9H2,1-2H3/t13-,15-/m1/s1
  • c2c3c1c(cccc1[nH]2)[C@H]4\C=C(/CN([C@@H]4C3)C)C
Properties
Chemical formula
 C16H18N2
Molar mass 238.334 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound

Agroclavine belongs to the group of ergot alkaloids, which also includes ergotamine.[1] Historically, the main use of agroclavine was in the synthesis of ergot-based drugs; agroclavine can be oxidized to elymoclavine, which then undergoes further processing.[2]

References

  1. ^ Bhattacharji, S., Birch, A. J., Brack, A., Hofmann, A., Kobel, H., Smith, D. C. C., Smith, Herchel, Winter J. (1962). "Biosynthesis. XXVII. The biosynthesis of ergot alkaloids". Journal of the Chemical Society: 421–425. doi:10.1039/jr9620000421.
  2. ^ Cordell GA (2002). The Alkaloids: Chemistry and Biology. Gulf Professional Publishing. pp. 6–. ISBN 978-0-12-469558-0.
  • v
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Lysergic acid
derivatives
Psychedelic
lysergamides
Clavines
Other
ergolines
Natural
sources

Morning glory: Argyreia nervosa (Hawaiian Baby Woodrose), Ipomoea spp.(Morning Glory, Tlitliltzin, Badoh Negro), Rivea corymbosa (Coaxihuitl, Ololiúqui)