Alizapride

Chemical compound
  • A03FA05 (WHO)
Legal statusLegal status
  • In general: ℞ (Prescription only)
Pharmacokinetic dataElimination half-life3 hoursExcretionRenalIdentifiers
  • N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
CAS Number
  • 59338-93-1 checkY
PubChem CID
  • 43008
DrugBank
  • DB01425 checkY
ChemSpider
  • 39202 checkY
UNII
  • P55703ZRZY
KEGG
  • D07102 checkY
ChEMBL
  • ChEMBL290194 checkY
ECHA InfoCard100.056.082 Edit this at WikidataChemical and physical dataFormulaC16H21N5O2Molar mass315.377 g·mol−13D model (JSmol)
  • Interactive image
  • C=CCN1CCCC1CNC(=O)c3cc2nn[nH]c2cc3OC
InChI
  • InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20) checkY
  • Key:KSEYRUGYKHXGFW-UHFFFAOYSA-N checkY
  (verify)

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

References

  1. ^ Ballatori E, Roila F (September 2003). "Impact of nausea and vomiting on quality of life in cancer patients during chemotherapy". Health and Quality of Life Outcomes. 1: 46. doi:10.1186/1477-7525-1-46. PMC 212194. PMID 14521717.
  • v
  • t
  • e
5-HT3 serotonin ion
channel antagonists5-HT serotonin G-protein
receptor antagonistsCB1 agonists
(cannabinoids)D2/D3 antagonistsH1 antagonists
(antihistamines)mACh antagonists
(anticholinergics)NK1 antagonistsOthers
  • v
  • t
  • e
Drugs for
functional
bowel
disorders
Antimuscarinics
Tertiary
amino group
Quaternary
ammonium
compounds
Phosphodiesterase
inhibitors
Acting on
serotonin receptors
Other
Belladonna
and derivatives
(antimuscarinics)
Propulsives
  • v
  • t
  • e
D1-like
Agonists
PAMs
Antagonists
D2-like
Agonists
Antagonists
  • See also: Receptor/signaling modulators
  • Adrenergics
  • Serotonergics
  • Monoamine reuptake inhibitors
  • Monoamine releasing agents
  • Monoamine metabolism modulators
  • Monoamine neurotoxins
Stub icon

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e