Asoxime chloride
Chemical compound
- none
- Experimental
- 4-carbamoyl-1-[({2-[(E)-(hydroxyimino)methyl]pyridinium-1-yl}methoxy)methyl]pyridinium dichloride
- 34433-31-3
N
- 5484128
- 13004322
Y
- HUV88P6SJS
- ChEMBL33051 Y
- Interactive image
- C1=CC=[N+](C(=C1)/C=N/O)COC[N+]2=CC=C(C=C2)C(=O)N.[Cl-].[Cl-]
InChI
- InChI=1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1HY
- Key:QELSIJXWEROXOE-UHFFFAOYSA-NY
N
Y (what is this?) (verify)Asoxime chloride, or more commonly HI-6, is a Hagedorn oxime used in the treatment of organophosphate poisoning.[1]
References
- ^ Cochran R, Kalisiak J, Küçükkilinç T, Radic Z, Garcia E, Zhang L, et al. (August 2011). "Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging". The Journal of Biological Chemistry. 286 (34): 29718–24. doi:10.1074/jbc.M111.264739. PMC 3191013. PMID 21730071.
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Antidotes (V03AB)
system
| Alcohol intoxication |
|
|---|---|
| Barbiturate overdose |
|
| Benzodiazepine overdose | |
| GHB overdose | |
| Nerve agent / Organophosphate poisoning |
|
| Opioid overdose | |
| Reversal of neuromuscular blockade |
system
| Beta blocker | |
|---|---|
| Digoxin toxicity | |
| Anticoagulants |
|
| Arsenic poisoning | |
|---|---|
| Cyanide poisoning |
|
| Hydrofluoric acid | |
| Methanol / Ethylene glycol poisoning |
|
| Paracetamol toxicity (Acetaminophen) | |
| Toxic metals (cadmium | |
| Other |
- Copper sulfate
- Ipecacuanha
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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