Betamethadol
Synthetic opioid analgesic drug
- None
- AU: S9 (Prohibited substance)
- BR: Class A1 (Narcotic drugs)[1]
- CA: Schedule I
- DE: Anlage I (Authorized scientific use only)
- US: Schedule I
- (3S,6R)-6-(dimethylamino)-4,4-diphenyl-3-heptanol
- 17199-55-2
- 10064061
- 8239601
- 57ANR1Z628
- D12675
- ChEMBL162243
- Interactive image
- O[C@H](C(c1ccccc1)(c2ccccc2)C[C@H](N(C)C)C)CC
InChI
- InChI=1S/C21H29NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17,20,23H,5,16H2,1-4H3/t17-,20+/m1/s1
- Key:QIRAYNIFEOXSPW-XLIONFOSSA-N
Betamethadol (INN), or β-methadol, also known as betametadol, is a synthetic opioid analgesic.[2] It is an isomer of dimepheptanol (methadol), the other being alphamethadol (α-methadol).[3] Betamethadol is composed of two isomers itself, L-β-methadol, and D-β-methadol.[3] Based on structure-activity relationships it can be inferred that both isomers are likely to be active as opioid analgesics, similarly to those of betacetylmethadol (β-acetylmethadol).[4]
See also
References
- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1294. ISBN 978-0-412-46630-4. Retrieved 15 May 2012.
- ^ a b United Nations Office on Drugs and Crime (2006). Dictionnaire Multilingue Des Stupéfiants Et Des Substances Psychotropes Placés Sous Contrôle International. United Nations Publications. p. 103. ISBN 978-92-1-048117-5. Retrieved 15 May 2012.
- ^ Newman JL, Vann RE, May EL, Beardsley PM (October 2002). "Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats". Psychopharmacology. 164 (1): 108–14. doi:10.1007/s00213-002-1198-8. PMID 12373424. S2CID 19815273.
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modulators
Calcium blockers |
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Sodium blockers |
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Potassium openers |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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