Butirosin
Antibiotic complex
- 12772-35-9 Y
- 72393
- 65326
- 8S52KR0L58
- C01559
- CHEBI:65109
- DTXSID60925967
- Interactive image
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InChI
- InChI=1S/C21H41N5O12/c22-2-1-8(28)19(34)26-7-3-6(24)17(37-20-11(25)15(32)13(30)9(4-23)35-20)18(12(7)29)38-21-16(33)14(31)10(5-27)36-21/h6-18,20-21,27-33H,1-5,22-25H2,(H,26,34)/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15+,16+,17+,18+,20+,21+/m0/s1
- Key:XEQLFNPSYWZPOW-NUOYRARPSA-N
Butirosin is an aminoglycoside antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirosin B being the major components.[2]
References
- ^ Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.
- ^ Elks J (2014). The Dictionary of Drugs. Springer. p. 198.
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Aminoglycosides (initiation inhibitors) |
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Tetracycline antibiotics (tRNA binding) |
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Steroid antibacterials |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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