CC-1088

Skeletal formula

CC-1088 is a thalidomide analogue inhibitor of phosphodiesterase 4 that was being developed up to 2005 by Celgene Corp., for treating of inflammatory diseases and myelodysplastic syndromes.[1] Apremilast (CC-10004) was found to be a preferable.[2]

See also

References

  1. ^ K. Dredge (May 2005). "CC-1088 Celgene". Current Opinion in Investigational Drugs. 6 (5): 513–7. PMID 15912966.
  2. ^ Molostvov G, Morris A, Rose P, Basu S, Muller G (February 2004). "The effects of selective cytokine inhibitory drugs (CC-10004 and CC-1088) on VEGF and IL-6 expression and apoptosis in myeloma and endothelial cell co-cultures". British Journal of Haematology. 124 (3): 366–75. doi:10.1046/j.1365-2141.2003.04777.x. PMID 14717786.

External links

  • NCI Thesaurus
  • v
  • t
  • e
Phosphodiesterase inhibitors
PDE1
  • MMPX
  • SCH-51866
  • Vinpocetine
PDE2
  • BAY 60-7550
  • Carbazeran
  • EHNA
  • Oxindole
  • PDP
PDE3
PDE4
PDE5PDE7PDE9PDE10
PDE11
BC11-38
Non-selectiveUnsorted
See also: Receptor/signaling modulators