CM156

Piperazine based chemical compound
CM156
Identifiers
  • 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione
PubChem CID
  • 17756659
ChemSpider
  • 23325411
Chemical and physical data
FormulaC21H31N3S2
Molar mass389.62 g·mol−1
3D model (JSmol)
  • Interactive image
  • c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4
InChI
  • InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
  • Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N

CM156[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine.

See also

  • 3C-PEP
  • MT-45

References

  1. ^ Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR (May 2010). "A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice". The Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. PMC 2872963. PMID 20100904.
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Sigma receptor modulators
σ1
σ2
Unsorted
See also: Receptor/signaling modulators
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