CNOT4 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1E4U, 1UR6 |
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Identifiers |
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Aliases | CNOT4, CLONE243, NOT4, NOT4H, CCR4-NOT transcription complex subunit 4 |
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External IDs | OMIM: 604911; MGI: 1859026; HomoloGene: 40870; GeneCards: CNOT4; OMA:CNOT4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 7 (human)[1] |
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| Band | 7q33 | Start | 135,361,795 bp[1] |
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End | 135,510,127 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 B1 | Start | 34,999,000 bp[2] |
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End | 35,110,659 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- Achilles tendon
- testicle
- gastrocnemius muscle
- parietal pleura
- corpus callosum
- internal globus pallidus
- sural nerve
- endothelial cell
- muscle of thigh
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| Top expressed in | - genital tubercle
- Rostral migratory stream
- tail of embryo
- zygote
- saccule
- primary oocyte
- secondary oocyte
- otic placode
- fossa
- otic vesicle
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - ubiquitin-protein transferase activity
- protein binding
- nucleic acid binding
- metal ion binding
- transferase activity
- RNA binding
| Cellular component | - cytosol
- cytoplasm
- CCR4-NOT complex
- nucleus
| Biological process | - protein ubiquitination
- nuclear-transcribed mRNA poly(A) tail shortening
- protein autoubiquitination
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
- ubiquitin-dependent protein catabolic process
- regulation of megakaryocyte differentiation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001008225 NM_001190847 NM_001190848 NM_001190849 NM_001190850
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NM_013316 NM_001393370 NM_001393371 NM_001393372 NM_001393373 NM_001393374 NM_001393375 |
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NM_001164411 NM_001164412 NM_001164413 NM_001164414 NM_016877 |
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RefSeq (protein) | NP_001008226 NP_001177776 NP_001177777 NP_001177778 NP_001177779
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NP_037448 |
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NP_001157883 NP_001157884 NP_001157885 NP_001157886 NP_058573 |
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Location (UCSC) | Chr 7: 135.36 – 135.51 Mb | Chr 6: 35 – 35.11 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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