Ciclindole
Chemical compound
- none
- In general: uncontrolled
- N,N-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-amine
- 32211-97-5
- 36082
- 33189
- CXJ7G6BYD7
- D03619
- ChEMBL2104160
- Interactive image
- c21c(cccc1)[nH]c3c2CC(N(C)C)CC3
Ciclindole (INN; WIN-27,147-2), also known as cyclindole (USAN), is an antipsychotic with a tricyclic structure that was never marketed.[1][2] It displaces spiperone binding in vitro and elevates dopamine levels in the striatum, indicating it acts as a D2 receptor antagonist.[2]
See also
References
- ^ Triggle DJ (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
- ^ a b Wood PL, McQuade PS (1984). "Ciclindole and flucindole: novel tetrahydrocarbazolamine neuroleptics". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8 (4–6): 773–7. doi:10.1016/0278-5846(84)90057-5. PMID 6152347. S2CID 39252411.
- v
- t
- e
- Butyrophenones: Benperidol
- Bromperidol
- Droperidol
- Haloperidol#
- Moperone
- Pipamperone
- Spiperone
- Timiperone
- Trifluperidol
- Phenothiazines: Acepromazine
- Acetophenazine
- Butaperazine
- Carphenazine (carfenazine)‡
- Chlorpromazine
- Cyamemazine
- Dixyrazine
- Fluphenazine
- Levomepromazine (methotrimeprazine)
- Mesoridazine
- Perazine
- Periciazine
- Perphenazine
- Piperacetazine
- Pipotiazine
- Prochlorperazine
- Promazine
- Sulforidazine
- Thiopropazate
- Thioproperazine
- Thioridazine
- Trifluoperazine
- Triflupromazine
- Others/unknown: Azacyclonol
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
