Clefamide

Chemical compound
  • P01AC02 (WHO)
Identifiers
  • 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
CAS Number
  • 3576-64-5
PubChem CID
  • 71819
ChemSpider
  • 64843 checkY
UNII
  • 4AZ2V8K4EK
KEGG
  • D07354 checkY
ChEMBL
  • ChEMBL1788400
CompTox Dashboard (EPA)
  • DTXSID30189296 Edit this at Wikidata
ECHA InfoCard100.020.631 Edit this at WikidataChemical and physical dataFormulaC17H16Cl2N2O5Molar mass399.22 g·mol−13D model (JSmol)
  • Interactive image
  • ClC(Cl)C(=O)N(CCO)Cc2ccc(Oc1ccc(cc1)[N+]([O-])=O)cc2
InChI
  • InChI=1S/C17H16Cl2N2O5/c18-16(19)17(23)20(9-10-22)11-12-1-5-14(6-2-12)26-15-7-3-13(4-8-15)21(24)25/h1-8,16,22H,9-11H2 checkY
  • Key:ODCUSWJXZDHLKV-UHFFFAOYSA-N checkY
  (verify)

Clefamide (trade name Mebinol) is an antiprotozoal agent that was used to treat amoebiasis in the 1960s.[1] There is no evidence for any later use of the drug.

References

  1. ^ Rodrigues LD, Jafferian PA, Vilella M, Costa AA, de Mello EB (November 1968). "[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin]". Hospital. 74 (5): 1563–73. PMID 5305335.
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Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
Entamoeba
Tissue amebicides
Nitroimidazole derivatives
Other
Luminal amebicides
Hydroxyquinoline derivatives
Dichloroacetamide derivatives
Aminoglycoside
Other/ungrouped
Acanthamoeba
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