Cormetasone

Chemical compound
Cormetasone
Clinical data
Other namesCormethasone; 6α,6β,9α-Trifluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16R,17R)-6,6,9-Trifluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthren-3-one
CAS Number
  • 35135-68-3
PubChem CID
  • 20055458
ChemSpider
  • 16736900
UNII
  • SKF3NCF20A
CompTox Dashboard (EPA)
  • DTXSID20188632 Edit this at Wikidata
Chemical and physical data
FormulaC22H27F3O5
Molar mass428.448 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@@H]1C[C@H]2[C@@H]3CC(C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)(F)F
InChI
  • InChI=1S/C22H27F3O5/c1-11-6-13-14-8-20(23,24)15-7-12(27)4-5-18(15,2)21(14,25)16(28)9-19(13,3)22(11,30)17(29)10-26/h4-5,7,11,13-14,16,26,28,30H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19+,21+,22+/m1/s1
  • Key:QVTPFMPYKMLGGK-QPZANWORSA-N

Cormetasone, or cormethasone, is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 315–. ISBN 978-1-4757-2085-3.


  • v
  • t
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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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