Cutaneous B-cell lymphoma

Medical condition
Cutaneous B-cell lymphoma
Cutaneous diffuse large B-cell lymphoma (DLBCL)
Cutaneous diffuse large B-cell lymphoma
SpecialtyDermatology/Oncology

Cutaneous B-cell lymphomas constitute a group of diseases that occur less commonly than cutaneous T-cell lymphoma, and are characterized histologically by B-cells that appear similar to those normally found in germinal centers of lymph nodes.[1]: 741  Conditions included in this group are:[1]: 740–743 

Signs and symptoms

Cutaneous B-cell lymphoma appears as single or many, often strongly consistent tumors, patches, plaques, and non-ulcerated nodules. While extracutaneous spread is a possibility, the disease usually stays restricted to the skin.[2]

Diagnosis

Using a biopsy of the skin lesions, histological and cytological analyses, as well as phenotypic and genotypic studies, the diagnosis is made.[2]

See also

References

  1. ^ a b James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ a b Lima, Margarida (2015). "Cutaneous primary B-cell lymphomas: from diagnosis to treatment". Anais Brasileiros de Dermatologia. 90 (5). FapUNIFESP (SciELO): 687–706. doi:10.1590/abd1806-4841.20153638. hdl:10400.16/1960. ISSN 0365-0596.

Further reading

  • Vitiello, Paola; Sica, Antonello; Ronchi, Andrea; Caccavale, Stefano; Franco, Renato; Argenziano, Giuseppe (2020-05-27). "Primary Cutaneous B-Cell Lymphomas: An Update". Frontiers in Oncology. 10. Frontiers Media SA. doi:10.3389/fonc.2020.00651. ISSN 2234-943X. PMC 7266949.
  • Gurumurthy, Ravichandran; Mohapatra, RanjanKumar; Easow, JoseM; Mohan, Subhashini (2015). "Cutaneous B cell lymphomas: Report of two interesting cases". Indian Journal of Dermatology. 60 (2). Medknow: 176. doi:10.4103/0019-5154.152521. ISSN 0019-5154. PMC 4372911.

External links

  • Mayo Clinic
  • Cleveland Clinic
Classification
D
  • ICD-11: 2A80.3 2A81.A 2A85.2
  • SNOMED CT: 402881008
External resources
  • eMedicine: article/1099540
  • Orphanet: 178563
  • Scholia: Q5196683
  • v
  • t
  • e
B cell
(lymphoma,
leukemia)
(most CD19
By
development/
marker
TdT+
CD5+
CD22+
CD79a+
RS (CD15+, CD30+)
PCDs/PP
(CD38+/CD138+)
  • see immunoproliferative immunoglobulin disorders
By infection
Cutaneous
T/NK
T cell
(lymphoma,
leukemia)
(most CD3
By
development/
marker
Cutaneous
MF+variants
Non-MF
Other
peripheral
By infection
NK cell/
(most CD56)
T or NK
Lymphoid+
myeloid
Lymphocytosis
Cutaneous lymphoid hyperplasia
General