Descinolone

Chemical compound
Descinolone
Clinical data
Other namesDesoxytriamcinolone; 21-Desoxytriamcinolone; 9α-Fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16R,17S)-17-Acetyl-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number
  • 595-52-8
PubChem CID
  • 250822
ChemSpider
  • 219695
UNII
  • FBV60529GN
KEGG
  • C15361
ChEBI
  • CHEBI:79863
ChEMBL
  • ChEMBL3250066
Chemical and physical data
FormulaC21H27FO5
Molar mass378.440 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)O
InChI
  • InChI=1S/C21H27FO5/c1-11(23)21(27)16(25)9-15-14-5-4-12-8-13(24)6-7-18(12,2)20(14,22)17(26)10-19(15,21)3/h6-8,14-17,25-27H,4-5,9-10H2,1-3H3/t14-,15-,16+,17-,18-,19-,20-,21+/m0/s1
  • Key:DYCBAFABWCTLEN-PMVIMZBYSA-N

Descinolone is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 362–. ISBN 978-1-4757-2085-3.


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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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