Diacetolol
Chemical compound
- none
- In general: ℞ (Prescription only)
- N-[3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
- 22568-64-5
- 50894
- 46139 Y
- 4ER0CZ5G7C
- ChEMBL2106189
- DTXSID70865421
- Interactive image
- O=C(Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C)C
InChI
- InChI=1S/C16H24N2O4/c1-10(2)17-8-14(21)9-22-16-6-5-13(18-12(4)20)7-15(16)11(3)19/h5-7,10,14,17,21H,8-9H2,1-4H3,(H,18,20) Y
- Key:AWOGXJOBNAWQSF-UHFFFAOYSA-N Y
Diacetolol is the primary metabolite of acebutolol. It is a beta blocker and anti-arrhythmic agent.[1]
References
- ^ Basil B, Jordan R (May 1982). "Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol". European Journal of Pharmacology. 80 (1): 47–56. doi:10.1016/0014-2999(82)90176-5. PMID 6124437.
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(antagonize α-adrenergic
vasoconstriction)
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Peripheral |
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Serotonin receptor antagonists | |
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Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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