Encainide
Chemical compound
- C01BC08 (WHO)
- Withdrawn
- 4-Methoxy-N-[2-(1-methyl-2-piperidin-1-ylethyl)phenyl]benzamide
- 66778-36-7 Y
- 48041
- DB01228 Y
- 43697 Y
- SY3J0147NB
- D07894 Y
- CHEBI:4788 Y
- ChEMBL315838 N
- DTXSID0022983
- Interactive image
- COc1ccc(C(=O)Nc2ccccc2CCC2CCCCN2C)cc1
InChI
- InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25) Y
- Key:PJWPNDMDCLXCOM-UHFFFAOYSA-N Y
Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects.[1]
Synthesis
See also
- Iferanserin
- Cardiac Arrhythmia Suppression Trial
References
- ^ Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH, et al. (March 1991). "Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial". The New England Journal of Medicine. 324 (12): 781–8. doi:10.1056/NEJM199103213241201. PMID 1900101.
- ^ Dykstra SJ, Minielli JL, Lawson JE, Ferguson HC, Dungan KW (September 1973). "Lysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidines". Journal of Medicinal Chemistry. 16 (9): 1015–20. doi:10.1021/jm00267a012. PMID 4745503.
- v
- t
- e
VGKCsTooltip Voltage-gated potassium channels |
| ||||
---|---|---|---|---|---|
IRKsTooltip Inwardly rectifying potassium channel |
| ||||
KCaTooltip Calcium-activated potassium channel |
| ||||
K2PsTooltip Tandem pore domain potassium channel |
|
VGSCsTooltip Voltage-gated sodium channels |
| ||||
---|---|---|---|---|---|
ENaCTooltip Epithelial sodium channel |
| ||||
ASICsTooltip Acid-sensing ion channel |
|
CaCCsTooltip Calcium-activated chloride channel |
| ||||
---|---|---|---|---|---|
CFTRTooltip Cystic fibrosis transmembrane conductance regulator |
| ||||
Unsorted |
|
TRPsTooltip Transient receptor potential channels |
|
---|---|
LGICsTooltip Ligand gated ion channels |
|
See also: Receptor/signaling modulators • Transient receptor potential channel modulators
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e