Endothion

Endothion
Names
Preferred IUPAC name
S-[(5-Methoxy-4-oxo-4H-pyran-2-yl)methyl] O,O-dimethyl phosphorothioate
Identifiers
CAS Number
  • 2778-04-3 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 16569
ECHA InfoCard 100.018.612 Edit this at Wikidata
PubChem CID
  • 17717
UNII
  • V047DQ6B7X checkY
CompTox Dashboard (EPA)
  • DTXSID2041911 Edit this at Wikidata
InChI
  • InChI=1S/C9H10NO3PS/c1-11-14(15,12-2)13-9-5-3-8(7-10)4-6-9/h3-6H,1-2H3 checkY
    Key: SCKHCCSZFPSHGR-UHFFFAOYSA-N checkY
  • InChI=1S/C9H13O6PS/c1-12-9-5-15-7(4-8(9)10)6-17-16(11,13-2)14-3/h4-5H,6H2,1-3H3
    Key: YCAGGFXSFQFVQL-UHFFFAOYSA-N
  • COC1=COC(=CC1=O)CSP(=O)(OC)OC
Properties
Chemical formula
C9H13O6PS
Molar mass 280.23 g·mol−1
Appearance White Crystals
Density 0.932 g/cm3
Melting point −7 to 96 °C; 19 to 205 °F; 266 to 369 K
Solubility in water
150 g/100 ml
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
3
0
0
Safety data sheet (SDS) [1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references
Chemical compound

Endothion is an organic compound used as an insecticide and acaricides. It is part of the chemical class of organophosphorus compounds. It is generally described as white crystals with a slight odor. It is used as an insecticide, but not sold in the United States or Canada.[2]

Synonyms

  • *2-(S-DIMETHYLPHOSPHOROTHIO- METHYL)-5-METHOXY-4-PYRONE
  • 5-METHOXY-2-(DIMETHOXYPHOSPHINYLTHIOMETHYL) PYRONE-4
  • AC-18737
  • ENDOCID
  • ENDOCIDE
  • ENT 24653
  • EXOTHION
  • FMC 5767
  • NIA 5767
  • NIAGARA 5767
  • O,O-DIMETHYL PHOSPHOROTHIOATE, S-ESTER WITH 2-(MERCAPTOMETHYL)-5-METHOXY-4H-PYRAN-4-ONE
  • O,O-DIMETHYL S-(5-METHOXY- 4-OXO-4H-PYRAN-2-YL) PHOSPHOROTHIOATE
  • O,O-DIMETHYL S-(5-METHOXYPYRONYL- 2-METHYL) THIOPHOSPHATE
  • PHOSPHATE 100
  • PHOSPHOPYRON
  • PHOSPHOPYRONE
  • PHOSPHOROTHIOIC ACID, O,O-DIMETHYL ESTER, S-ESTER WITH 2-(MERCAPTOMETHYL)-5-METHOXY-4H-PYRAN-4-ONE
  • PHOSPHOROTHIOIC ACID, S-((5-METHOXY-4-OXO-4H-PYRAN-2-YL)METHYL) O,O-DIMETHYL ESTER
  • S-(5-METHOXY-4-PYRON-2-YLMETHYL) DIMETHYL PHOSPHOROTHIOATE
  • S-5-METHOXY-4-OXOPYRAN-2-YLMETHYL DIMETHYL PHOSPHOROTHIOATE
  • S-5-METHOXY-4-PYRON-2-YLMETHYL O,O-DIMETHYL PHOSPHOROTHIOATE
  • S-[(5-METHOXY-4-OXO-4H-PYRAN-2-YL)METHYL] O,O-DIMETHYL PHOSPHOROTHIOATE

Safety

Endothion can enter the body via inhalation, ingestion, and contact with the skin and eyes. Symptoms of endothion poisoning include dyspnea, rales, diarrhea, bronchospasm, bronchorrhea, tachypnea, and opsoclonus, Noncardiacogenic Pulmonary Edema, Salivation.[1]

References

  1. ^ a b "Material Safety Data Sheets: Endothion" (PDF). Central Pollution Control Board, Ministry of Environment & Forests, Government of India. Archived from the original (PDF) on 2010-12-15. Retrieved 2011-12-09.
  2. ^ "Endothion". CAMEO Chemicals. Retrieved 2011-11-09.

External links

  • v
  • t
  • e
CarbamatesInorganic compoundsInsect growth regulatorsNeonicotinoidsOrganochloridesOrganophosphorusPyrethroidsRyanoidsOther chemicalsMetabolitesBiopesticides
  • v
  • t
  • e
Enzyme
(modulators)
ChATTooltip Choline acetyltransferase
  • Inhibitors: 1-(-Benzoylethyl)pyridinium
  • 2-(α-Naphthoyl)ethyltrimethylammonium
  • 3-Chloro-4-stillbazole
  • 4-(1-Naphthylvinyl)pyridine
  • Acetylseco hemicholinium-3
  • Acryloylcholine
  • AF64A
  • B115
  • BETA
  • CM-54,903
  • N,N-Dimethylaminoethylacrylate
  • N,N-Dimethylaminoethylchloroacetate
AChETooltip Acetylcholinesterase
BChETooltip Butyrylcholinesterase
Transporter
(modulators)
CHTTooltip Choline transporter
VAChTTooltip Vesicular acetylcholine transporter
Release
(modulators)
Inhibitors
  • SNAP-25Tooltip Synaptosomal-associated protein 25 inactivators: Botulinum toxin (A, C, E)
  • VAMPTooltip Vesicle-associated membrane protein inactivators: Botulinum toxin (B, D, F, G)
Enhancers
See also
Receptor/signaling modulators
Muscarinic acetylcholine receptor modulators
Nicotinic acetylcholine receptor modulators