ESRRB |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2, estrogen related receptor beta, ERRbeta2, ERR beta-2, Esrrb |
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External IDs | OMIM: 602167 MGI: 1346832 HomoloGene: 69108 GeneCards: ESRRB |
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Gene location (Human) |
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| Chr. | Chromosome 14 (human)[1] |
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| Band | 14q24.3 | Start | 76,310,712 bp[1] |
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End | 76,501,837 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 12 (mouse)[2] |
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| Band | 12 D2|12 40.49 cM | Start | 86,407,891 bp[2] |
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End | 86,568,402 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - kidney
- gastrocnemius muscle
- left ventricle
- renal medulla
- body of stomach
- skeletal muscle tissue
- retinal pigment epithelium
- fundus
- ganglionic eminence
- prefrontal cortex
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| Top expressed in | - stria vascularis
- retinal pigment epithelium
- morula
- blastocyst
- secondary oocyte
- ooblast
- urethra
- male urethra
- ampulla of semicircular canal
- outer nuclear layer
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - steroid binding
- nuclear receptor activity
- zinc ion binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA binding
- sequence-specific DNA binding
- transcription factor binding
- metal ion binding
- steroid hormone receptor activity
- transcription coactivator activity
- protein binding
- RNA polymerase II complex binding
- cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- DNA-binding transcription factor activity
- transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
| Cellular component | - nucleus
- nucleoplasm
- condensed chromosome
- integrator complex
- chromosome
- cytoplasm
| Biological process | - regulation of transcription, DNA-templated
- positive regulation of transcription by RNA polymerase II
- embryonic placenta development
- transcription, DNA-templated
- steroid hormone mediated signaling pathway
- transcription initiation from RNA polymerase II promoter
- intracellular receptor signaling pathway
- stem cell population maintenance
- negative regulation of transcription by RNA polymerase II
- cell population proliferation
- stem cell division
- cell dedifferentiation
- photoreceptor cell maintenance
- positive regulation of transcription, DNA-templated
- inner ear development
- positive regulation of transcription involved in G1/S transition of mitotic cell cycle
- positive regulation of transcription involved in G2/M transition of mitotic cell cycle
- positive regulation of stem cell population maintenance
- regulation of stem cell division
- negative regulation of stem cell differentiation
- positive regulation of glycogen biosynthetic process
- positive regulation of glycolytic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 14: 76.31 – 76.5 Mb | Chr 12: 86.41 – 86.57 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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