Eticlopride
Chemical compound
- none
- 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide
- 84226-12-0
Y - HCl: 97612-24-3 Y
- 57267
- 966
- 51626
N
- J8M468HBH4
- HCl: HJ2CAH4TZ1 Y
- ChEMBL8946 N
- DTXSID9048435
- Interactive image
- CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
N
Y (what is this?) (verify)Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research.[1][2][3][4]
References
- ^ "Eticlopride hydrochloride". Abcam.
- ^ Claytor R, Lile JA, Nader MA (March 2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys". Pharmacology, Biochemistry, and Behavior. 83 (3): 456–64. doi:10.1016/j.pbb.2006.03.007. PMID 16631246. S2CID 39482275.
- ^ Hemby SE, Smith JE, Dworkin SI (June 1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats". The Journal of Pharmacology and Experimental Therapeutics. 277 (3): 1247–58. PMID 8667185.
- ^ Haile CN, Kosten TA (November 2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats". The Journal of Pharmacology and Experimental Therapeutics. 299 (2): 509–18. PMID 11602661.
External links
- Eticlopride at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Dopamine receptor modulators
- See also: Receptor/signaling modulators
- Adrenergics
- Serotonergics
- Monoamine reuptake inhibitors
- Monoamine releasing agents
- Monoamine metabolism modulators
- Monoamine neurotoxins
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