Etiprednol

Chemical compound
Etiprednol
Clinical data
Other names11β,17α,Dihydroxy-21-oxa-21-ethylpregna-1,4-diene-3,20-dione; Ethyl 11β,17α-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • Ethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
CAS Number
  • 182069-13-2
PubChem CID
  • 11462974
UNII
  • 08052A2L6I
CompTox Dashboard (EPA)
  • DTXSID30171237 Edit this at Wikidata
Chemical and physical data
FormulaC22H30O5
Molar mass374.477 g·mol−1
3D model (JSmol)
  • Interactive image
  • CCOC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)O
InChI
  • InChI=1S/C22H30O5/c1-4-27-19(25)22(26)10-8-16-15-6-5-13-11-14(23)7-9-20(13,2)18(15)17(24)12-21(16,22)3/h7,9,11,15-18,24,26H,4-6,8,10,12H2,1-3H3/t15-,16-,17-,18+,20-,21-,22-/m0/s1
  • Key:JTXYEERBIZXLJC-DCJXKKNWSA-N

Etiprednol is a synthetic glucocorticoid corticosteroid.[1][2]

References

  1. ^ Patrick G (20 April 2017). An Introduction to Medicinal Chemistry. Oxford University Press. pp. 772–. ISBN 978-0-19-874969-1.
  2. ^ Lamberth C, Dinges J (17 May 2016). Bioactive Carboxylic Compound Classes: Pharmaceuticals and Agrochemicals. Wiley. pp. 260–. ISBN 978-3-527-69396-2.


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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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