Felbinac
Topical NSAID medication
- M02AA08 (WHO)
- UK: P (Pharmacy medicines)
- biphenyl-4-ylacetic acid
- 5728-52-9
- 3332
- DB07477
Y
- 3215 Y
- 94WNJ5U8L7
- D01675 Y
- CHEBI:31597 Y
- ChEMBL413965 Y
- DTXSID0045389
- Interactive image
- O=C(O)Cc1ccc(cc1)c2ccccc2
InChI
- InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)Y
- Key:QRZAKQDHEVVFRX-UHFFFAOYSA-NY
Felbinac (INN, or biphenylylacetic acid) is a topical medicine,[1] belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.[2] It is an active metabolite of fenbufen.[3]
Related compounds
The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.
See also
References
- ^ The Merck Index, 12th Edition. 3989
- ^ Description of Felbinac on Tiscali [1]
- ^ Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.
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pyrazolidines
and related substances
- Aceclofenac
- Acemetacin
- Alclofenac
- Amfenac
- Bendazac
- Bromfenac
- Bufexamac
- Bumadizone
- Diclofenac
- Difenpiramide
- Etodolac
- Felbinac
- Fenclozic acid
- Fentiazac
- Indometacin
- Indometacin farnesil
- Isoxepac
- Ketorolac
- Lonazolac
- Mofezolac
- Oxametacin
- Prodolic acid
- Proglumetacin
- Sulindac
- Tiopinac
- Tolmetin
- Zomepirac†
- Ampiroxicam
- Droxicam
- Isoxicam
- Lornoxicam
- Meloxicam
- Piroxicam
- Pivoxicam
- Tenoxicam
derivatives (profens)
- Alminoprofen
- Benoxaprofen†
- Carprofen‡
- Dexibuprofen
- Dexketoprofen
- Fenbufen
- Fenoprofen
- Flunoxaprofen
- Flurbiprofen
- Ibuprofen#
- Ibuproxam
- Indoprofen†
- Ketoprofen
- Loxoprofen
- Miroprofen
- Naproxen
- Oxaprozin
- Pelubiprofen
- Piketoprofen
- Pirprofen
- Suprofen
- Tarenflurbil
- Tepoxalin‡
- Tiaprofenic acid
- Vedaprofen‡
- Zaltoprofen
- COX-inhibiting nitric oxide donator: Naproxcinod
acids (fenamates)
(coxibs)
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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