Fendiline

Non-selective calcium channel blocker
  • C08EA01 (WHO)
Identifiers
  • 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine
CAS Number
  • 13042-18-7 checkY
PubChem CID
  • 3336
DrugBank
  • DB08980 ☒N
ChemSpider
  • 3219 ☒N
UNII
  • S253D559A8
KEGG
  • D07185 checkY
ChEMBL
  • ChEMBL254832 ☒N
CompTox Dashboard (EPA)
  • DTXSID5048473 Edit this at Wikidata
ECHA InfoCard100.032.635 Edit this at WikidataChemical and physical dataFormulaC23H25NMolar mass315.460 g·mol−13D model (JSmol)
  • Interactive image
  • CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3
InChI
  • InChI=1S/C23H25N/c1-19(20-11-5-2-6-12-20)24-18-17-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22/h2-16,19,23-24H,17-18H2,1H3 ☒N
  • Key:NMKSAYKQLCHXDK-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Fendiline is a nonselective calcium channel blocker.[1][2]

References

  1. ^ Scultéty S, Tamáskovits E (1991). "Effect of Ca2+ antagonists on isolated rabbit detrusor muscle". Acta Physiologica Hungarica. 77 (3–4): 269–78. PMID 1755331.
  2. ^ "Fendiline - an overview | ScienceDirect Topics".
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Ion channel modulators
Calcium
VDCCsTooltip Voltage-dependent calcium channels
Blockers
Activators
Potassium
VGKCsTooltip Voltage-gated potassium channels
Blockers
Activators
IRKsTooltip Inwardly rectifying potassium channel
Blockers
Activators
  • GIRKTooltip G protein-coupled inwardly rectifying potassium channel-specific: ML-297 (VU0456810)
KCaTooltip Calcium-activated potassium channel
Blockers
  • BKCa-specific: Ethanol (alcohol)
  • GAL-021
Activators
K2PsTooltip Tandem pore domain potassium channel
Blockers
Activators
Sodium
VGSCsTooltip Voltage-gated sodium channels
Blockers
Activators
ENaCTooltip Epithelial sodium channel
Blockers
Activators
  • Solnatide
ASICsTooltip Acid-sensing ion channel
Blockers
Chloride
CaCCsTooltip Calcium-activated chloride channel
Blockers
Activators
CFTRTooltip Cystic fibrosis transmembrane conductance regulator
Blockers
Activators
Unsorted
Blockers
Others
TRPsTooltip Transient receptor potential channels
  • See here instead.
LGICsTooltip Ligand gated ion channels
  • See here instead.
See also: Receptor/signaling modulators • Transient receptor potential channel modulators
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