Foveola

Foveola
Details
Identifiers
Latinfoveola
TA98A15.2.04.023
TA26786
FMA77666
Anatomical terminology
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The foveola is located within a region called the macula, a yellowish, cone photoreceptor filled portion of the human retina. Approximately 0.35 mm in diameter, the foveola lies in the center of the fovea and contains only cone cells and a cone-shaped zone of Müller cells.[1] In this region the cone receptors are found to be longer, slimmer, and more densely packed than anywhere else in the retina, thus allowing that region to have the potential to have the highest visual acuity in the eye.

The center of the foveola is sometimes referred to as the umbo, a small (150-200µm) center of the floor of the foveola; features elongated cones. The umbo is the observed point corresponding to the normal light reflex but not solely responsible for this light reflex.

The anatomy of the foveola was recently reinvestigated.[2]

Serial semithin and ultrathin sections, and focused ion beam (FIB) tomography were prepared from 32 foveolae from monkeys (Macaca fascicularis) and humans. Serial sections and FIB analysis were then used to construct 3D models of central Müller and photoreceptor cells.[2]

It was discovered that in monkeys, outer segments of central foveolar cones are twice as long as those from parafoveal cones and do not run completely parallel to the incident light. Unique Müller cells are present in the central foveolae (area of 200 μm in diameter) of humans and monkeys.[2]

Photograph of the retina of the human eye, with overlay diagrams showing the positions and sizes of the macula, fovea, and optic disc

Additional images

  • Schematic diagram of the macula lutea of the retina, showing perifovea, parafovea, fovea, and clinical macula
    Schematic diagram of the macula lutea of the retina, showing perifovea, parafovea, fovea, and clinical macula
  • Time-Domain OCT of the macular area of a retina at 800 nm, axial resolution 3 µm
    Time-Domain OCT of the macular area of a retina at 800 nm, axial resolution 3 µm
  • Spectral-Domain OCT macula cross-section scan.
    Spectral-Domain OCT macula cross-section scan.
  • macula histology (OCT)
    macula histology (OCT)
  • A fundus photograph showing the macula as a spot to the left. The optic disc is the area on the right where blood vessels converge. The grey, more diffuse spot in the centre is a shadow artifact.
    A fundus photograph showing the macula as a spot to the left. The optic disc is the area on the right where blood vessels converge. The grey, more diffuse spot in the centre is a shadow artifact.

Notes

  1. ^ Gass, J. Donald M (1999). "Müller Cell Cone, an Overlooked Part of the Anatomy of the Fovea Centralis". Archives of Ophthalmology. 117 (6): 821–3. doi:10.1001/archopht.117.6.821. PMID 10369597.
  2. ^ a b c Tschulakow, Alexander V; Oltrup, Theo; Bende, Thomas; Schmelzle, Sebastian; Schraermeyer, Ulrich (2018). "The anatomy of the foveola reinvestigated". PeerJ. 6: e4482. doi:10.7717/peerj.4482. PMC 5853608. PMID 29576957. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
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Anatomy of the globe of the human eye
Fibrous tunic
(outer)
Sclera
  • Episcleral layer
  • Schlemm's canal
  • Trabecular meshwork
Cornea
1:posterior segment 2:ora serrata 3:ciliary muscle 4:ciliary zonules 5:Schlemm's canal 6:pupil 7:anterior chamber 8:cornea 9:iris 10:lens cortex 11:lens nucleus 12:ciliary process 13:conjunctiva 14:inferior oblique muscule 15:inferior rectus muscule 16:medial rectus muscle 17:retinal arteries and veins 18:optic disc 19:dura mater 20:central retinal artery 21:central retinal vein 22:optic nerve 23:vorticose vein 24:bulbar sheath 25:macula 26:fovea 27:sclera 28:choroid 29:superior rectus muscle 30:retina1: posterior segment2: ora serrata3: ciliary muscle4: ciliary zonules5: Schlemm's canal6: pupil7: anterior chamber8: cornea9: iris10: lens cortex11: lens nucleus12: ciliary process13: conjunctiva14: inferior oblique muscule15: inferior rectus muscule16: medial rectus muscle17: retinal arteries and veins18: optic disc19: dura mater20: central retinal artery21: central retinal vein22: optic nerve23: vorticose vein24: bulbar sheath25: macula26: fovea27: sclera28: choroid29: superior rectus muscle30: retina
1:posterior segment 2:ora serrata 3:ciliary muscle 4:ciliary zonules 5:Schlemm's canal 6:pupil 7:anterior chamber 8:cornea 9:iris 10:lens cortex 11:lens nucleus 12:ciliary process 13:conjunctiva 14:inferior oblique muscule 15:inferior rectus muscule 16:medial rectus muscle 17:retinal arteries and veins 18:optic disc 19:dura mater 20:central retinal artery 21:central retinal vein 22:optic nerve 23:vorticose vein 24:bulbar sheath 25:macula 26:fovea 27:sclera 28:choroid 29:superior rectus muscle 30:retina
Uvea / vascular
tunic (middle)
Choroid
Ciliary body
Iris
Retina (inner)
Layers
Cells
Other
Anatomical regions
of the eye
Anterior segment
Posterior segment
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