GPR171

Protein-coding gene in the species Homo sapiens
GPR171
Identifiers
AliasesGPR171, H963, G protein-coupled receptor 171
External IDsMGI: 2442043 HomoloGene: 36330 GeneCards: GPR171
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for GPR171
Genomic location for GPR171
Band3q25.1Start151,197,832 bp[1]
End151,203,216 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for GPR171
Genomic location for GPR171
Band3|3 DStart59,003,869 bp[2]
End59,009,242 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • appendix

  • blood

  • lymph node

  • spleen

  • superficial temporal artery

  • amniotic fluid

  • gallbladder

  • rectum

  • visceral pleura

  • left uterine tube
Top expressed in
  • blood

  • spleen

  • thymus

  • morula

  • subcutaneous adipose tissue

  • bone marrow

  • blastocyst

  • jejunum

  • right lung lobe

  • duodenum
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled purinergic nucleotide receptor activity
  • G protein-coupled receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • integral component of plasma membrane
  • membrane
Biological process
  • G protein-coupled receptor signaling pathway
  • negative regulation of myeloid cell differentiation
  • signal transduction
  • G protein-coupled purinergic nucleotide receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

29909

229323

Ensembl

ENSG00000174946

ENSMUSG00000050075

UniProt

O14626

Q8BG55

RefSeq (mRNA)

NM_013308

NM_173398

RefSeq (protein)

NP_037440

NP_775574

Location (UCSC)Chr 3: 151.2 – 151.2 MbChr 3: 59 – 59.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 171 is a protein that in humans is encoded by the GPR171 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174946 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050075 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jacobs KA, Collins-Racie LA, Colbert M, Duckett M, Golden-Fleet M, Kelleher K, Kriz R, LaVallie ER, Merberg D, Spaulding V, Stover J, Williamson MJ, McCoy JM (Dec 1997). "A genetic selection for isolating cDNAs encoding secreted proteins". Gene. 198 (1–2): 289–96. doi:10.1016/S0378-1119(97)00330-2. PMID 9370294.
  6. ^ "Entrez Gene: GPR171 G protein-coupled receptor 171".

Further reading

  • Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
  • Joensuu T, Hämäläinen R, Yuan B, et al. (2001). "Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3". Am. J. Hum. Genet. 69 (4): 673–84. doi:10.1086/323610. PMC 1226054. PMID 11524702.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • v
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Neurotransmitter
Adrenergic
Purinergic
Serotonin
Other
Metabolites and
signaling molecules
Eicosanoid
Other
Peptide
Neuropeptide
Other
Miscellaneous
Taste, bitter
Orphan
Other
Adhesion
Orphan
Other
Taste, sweet
Other
Class F: Frizzled & Smoothened
Frizzled
Smoothened
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