GPR25

Protein-coding gene in the species Homo sapiens
GPR25
Identifiers
AliasesGPR25, G protein-coupled receptor 25
External IDsOMIM: 602174 MGI: 2686146 HomoloGene: 3872 GeneCards: GPR25
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for GPR25
Genomic location for GPR25
Band1q32.1Start200,872,981 bp[1]
End200,874,178 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for GPR25
Genomic location for GPR25
Band1|1 E4Start136,187,535 bp[2]
End136,188,611 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • blood

  • appendix

  • right uterine tube

  • body of stomach

  • spleen

  • fundus

  • upper lobe of left lung

  • face

  • pharynx

  • thymus
Top expressed in
  • prefrontal cortex

  • nucleus accumbens

  • visual cortex

  • subiculum

  • hippocampus proper

  • temporal lobe

  • piriform cortex

  • cerebellum

  • stria vascularis

  • spinal cord
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • protein binding
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • integral component of plasma membrane
  • membrane
Biological process
  • G protein-coupled receptor signaling pathway
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2848

383563

Ensembl

ENSG00000170128

ENSMUSG00000052759

UniProt

O00155

P0C5I1

RefSeq (mRNA)

NM_005298

NM_001101516

RefSeq (protein)

NP_005289

NP_001094986

Location (UCSC)Chr 1: 200.87 – 200.87 MbChr 1: 136.19 – 136.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 25 is a protein that in humans is encoded by the GPR25 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170128 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052759 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jung BP, Nguyen T, Kolakowski LF Jr, Lynch KR, Heng HH, George SR, O'Dowd BF (Feb 1997). "Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1". Biochem Biophys Res Commun. 230 (1): 69–72. doi:10.1006/bbrc.1996.5828. PMID 9020062.
  6. ^ "Entrez Gene: GPR25 G protein-coupled receptor 25".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Sherva R, Miller MB, Lynch AI, et al. (2007). "A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study". Am. J. Hypertens. 20 (4): 398–402. doi:10.1016/j.amjhyper.2006.10.001. PMC 1997287. PMID 17386346.
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Class F: Frizzled & Smoothened
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