GPR27

Protein-coding gene in the species Homo sapiens
GPR27
Identifiers
AliasesGPR27, SREB1, G protein-coupled receptor 27
External IDsOMIM: 605187 MGI: 1202299 HomoloGene: 7344 GeneCards: GPR27
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for GPR27
Genomic location for GPR27
Band3p13Start71,753,855 bp[1]
End71,756,496 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for GPR27
Genomic location for GPR27
Band6|6 D3Start99,669,640 bp[2]
End99,672,027 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • internal globus pallidus

  • endothelial cell

  • superior vestibular nucleus

  • Brodmann area 23

  • subthalamic nucleus

  • inferior ganglion of vagus nerve

  • nucleus accumbens

  • spinal cord

  • caudate nucleus

  • entorhinal cortex
Top expressed in
  • olfactory tubercle

  • nucleus accumbens

  • fossa

  • substantia nigra

  • ventromedial nucleus

  • vas deferens

  • Region I of hippocampus proper

  • subiculum

  • condyle

  • supraoptic nucleus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • signal transducer activity
  • G protein-coupled receptor activity
Cellular component
  • integral component of membrane
  • membrane
  • plasma membrane
Biological process
  • positive regulation of insulin secretion involved in cellular response to glucose stimulus
  • positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
  • signal transduction
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2850

14761

Ensembl

ENSG00000170837

ENSMUSG00000072875

UniProt

Q9NS67

O54897

RefSeq (mRNA)

NM_018971

NM_008158

RefSeq (protein)

NP_061844

NP_032184

Location (UCSC)Chr 3: 71.75 – 71.76 MbChr 6: 99.67 – 99.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 27 is a protein that in humans is encoded by the GPR27 gene.[5][6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170837 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000072875 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
  6. ^ "Entrez Gene: GPR27 G protein-coupled receptor 27".
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