HTR3D

Protein-coding gene in the species Homo sapiens
HTR3D
Identifiers
AliasesHTR3D, 5HT3D, 5-hydroxytryptamine receptor 3D
External IDsOMIM: 610122 GeneCards: HTR3D
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for HTR3D
Genomic location for HTR3D
Band3q27.1Start184,031,544 bp[1]
End184,039,369 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • reproductive system

  • reproductive organ

  • gonad
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • extracellular ligand-gated ion channel activity
  • serotonin-gated cation-selective channel activity
  • ion channel activity
  • transmembrane signaling receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
  • integral component of plasma membrane
  • neuron projection
  • synapse
Biological process
  • ion transport
  • signal transduction
  • ion transmembrane transport
  • serotonin receptor signaling pathway
  • chemical synaptic transmission
  • regulation of membrane potential
  • nervous system process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

200909

n/a

Ensembl

ENSG00000186090

n/a

UniProt

Q70Z44

n/a

RefSeq (mRNA)

NM_182537
NM_001145143
NM_001163646

n/a

RefSeq (protein)

NP_001138615
NP_001157118
NP_872343

n/a

Location (UCSC)Chr 3: 184.03 – 184.04 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

5-hydroxytryptamine receptor 3D is a protein that in humans is encoded by the HTR3D gene.[3] The protein encoded by this gene is a subunit of the 5-HT3 receptor.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186090 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3". Gene. 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179.

External links

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