Hippocampal sulcus

Hippocampal sulcus
Hippocampal sulcus labeled at center.
Details
Identifiers
Latin	sulcus hippocampalis, sulcus hippocampi
NeuroNames	42
NeuroLex ID	birnlex_4004
TA98	A14.1.09.236
TA2	5522
FMA	83747
Anatomical terms of neuroanatomy [edit on Wikidata]

The hippocampal sulcus, also known as the hippocampal fissure, is a sulcus that separates the dentate gyrus from the subiculum and the CA1 field in the hippocampus.

Structure

Development

During human fetal development, the hippocampal sulcus first appears at approximately 10 weeks of gestational age. At this stage it exists as a broad shallow fissure along the surface of the dentate gyrus. Gradually, the fissure deepens and shifts toward the cornu ammonis. After about 18 weeks, the walls of the fissure fold into each other and begin to fuse. By 30 weeks, the hippocampal sulcus is normally obliterated except for its most medial part, leaving a shallow surface indentation.^[1]

Clinical significance

Enlargement of the hippocampal sulcus has been associated with medial temporal lobe atrophy occurring in Alzheimer's disease.^[2]

References

^ Humphrey, Tryphena. "The development of the human hippocampal fissure". Journal of anatomy. 1967 September; 101(Pt 4): 655–676.
^ Bastos-Leite AJ, van Waesberghe JH, Oen AL, van der Flier WM, Scheltens P, Barkhof F (2006). "Hippocampal sulcus width and cavities: comparison between patients with Alzheimer disease and nondemented elderly subjects". American Journal of Neuroradiology. 27 (10): 2141–5. PMC 7977199. PMID 17110684.

External links

Wikimedia Commons has media related to Hippocampal sulcus.

NIF Search - Hippocampal sulcus via the Neuroscience Information Framework

Anatomy of the cerebral cortex of the human brain

Frontal lobe

Superolateral

Prefrontal	Superior frontal gyrus 4 6 8 Middle frontal gyrus 9 10 46 Inferior frontal gyrus: 11 47-Pars orbitalis Broca's area 44-Pars opercularis 45-Pars triangularis Superior frontal sulcus Inferior frontal sulcus
Precentral	Precentral gyrus Precentral sulcus

Medial/inferior

Prefrontal	Superior frontal gyrus 4 6 Medial frontal gyrus 8 9 Paraterminal gyrus/Paraolfactory area 12 Straight gyrus 11 Orbital gyri/Orbitofrontal cortex 10 11 12 Ventromedial prefrontal cortex 10 Subcallosal area 25 Olfactory sulcus Orbital sulcus
Precentral	Paracentral lobule 4 Paracentral sulcus

Both

Parietal lobe

Superolateral	Superior parietal lobule 5 7 Inferior parietal lobule 40-Supramarginal gyrus 39-Angular gyrus Parietal operculum 43 Intraparietal sulcus
Medial/inferior	Paracentral lobule 1 2 3 5 Precuneus 7 Marginal sulcus
Both	Postcentral gyrus/Primary somatosensory cortex 3, 1 and 2 Secondary somatosensory cortex 5 Posterior parietal cortex 7

Occipital lobe

Superolateral	Occipital pole of cerebrum Occipital gyri Lateral occipital gyrus 18 19 Lunate sulcus Transverse occipital sulcus
Medial/inferior	Visual cortex 17 Cuneus Lingual gyrus Calcarine sulcus

Temporal lobe

Superolateral	Transverse temporal gyrus/Auditory cortex 41 and 42 Superior temporal gyrus 38 22/Wernicke's area (Planum temporale) Superior temporal sulcus Middle temporal gyrus 21
Medial/inferior	Occipitotemporal sulcus Fusiform gyrus 37 Medial temporal lobe 27 28 34 35 36 Inferior temporal sulcus Inferior temporal gyrus 20

Interlobar
sulci/fissures

Superolateral	Central (frontal+parietal) Lateral (frontal+parietal+temporal) Parieto-occipital Preoccipital notch
Medial/inferior	Longitudinal fissure Cingulate (frontal+cingulate) Collateral (temporal+occipital) Callosal sulcus

Limbic lobe

Parahippocampal gyrus	anterior Entorhinal cortex Perirhinal cortex Postrhinal cortex Posterior parahippocampal gyrus Prepyriform area
Cingulate cortex/gyrus	Subgenual area 25 Anterior cingulate 24 32 33 Posterior cingulate 23 31 Isthmus of cingulate gyrus: Retrosplenial cortex 26 29 30
Hippocampal formation	Hippocampal sulcus Fimbria of hippocampus Dentate gyrus Rhinal sulcus
Other	Indusium griseum Uncus Amygdala