Immethridine

Immethridine
Names
Preferred IUPAC name
4-[(1H-Imidazol-5-yl)methyl]pyridine
Identifiers
CAS Number
  • 87976-03-2 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL82298 ☒N
ChemSpider
  • 8165087 ☒N
ECHA InfoCard 100.163.679 Edit this at Wikidata
IUPHAR/BPS
  • 4024
PubChem CID
  • 9989505
UNII
  • F8ZT2IBM1X checkY
CompTox Dashboard (EPA)
  • DTXSID70587878 Edit this at Wikidata
InChI
  • InChI=1S/C9H9N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h1-4,6-7H,5H2,(H,11,12) ☒N
    Key: DFVSGZHJSIEEQQ-UHFFFAOYSA-N ☒N
  • InChI=1/C9H9N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h1-4,6-7H,5H2,(H,11,12)
    Key: DFVSGZHJSIEEQQ-UHFFFAOYAF
  • C1=CN=CC=C1CC2=CN=CN2
Properties
Chemical formula
 C9H9N3
Molar mass 159.188 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound

Immethridine is a histamine agonist selective for the H3 subtype.[1]

References

  1. ^ Kitbunnadaj, R; Zuiderveld, OP; Christophe, B; Hulscher, S; Menge, WM; Gelens, E; Snip, E; Bakker, RA; et al. (2004). "Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H(3) receptor agonist". Journal of Medicinal Chemistry. 47 (10): 2414–7. doi:10.1021/jm049932u. PMID 15115383.
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Histamine receptor modulators
H1
Agonists
  • 2-Pyridylethylamine
  • Betahistine
  • Histamine
  • HTMT
  • L-Histidine
  • UR-AK49
Antagonists
  • Unknown/unsorted: Azanator
  • Belarizine
  • Elbanizine
  • Flotrenizine
  • GSK1004723
  • Napactadine
  • Tagorizine
  • Trelnarizine
  • Trenizine
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors


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