Itramin tosilate
Chemical compound
- C01DX01 (WHO)
- 2-aminoethyl nitrate; 4-methylbenzenesulfonic acid
- 13445-63-1
Y
- 26000
- DBSALT002523
- 24219
- W9H0R50KY0
- D07157
- CHEBI:136001
- ChEMBL2106780
- DTXSID30158705
- Interactive image
- CC1=CC=C(C=C1)S(=O)(=O)O.C(CO[N+](=O)[O-])N
InChI
- InChI=1S/C7H8O3S.C2H6N2O3/c1-6-2-4-7(5-3-6)11(8,9)10;3-1-2-7-4(5)6/h2-5H,1H3,(H,8,9,10);1-3H2
- Key:HPPBBWMYZVALRK-UHFFFAOYSA-N
Itramin tosilate (INN), or itramin tosylate (more commonly), is a vasodilator.[1][2][3][4][5][6]
References
- ^ Batterman RC, Mouratoff GJ (June 1963). "Anginal syndrome. Treatment with a long-acting nitrate (itramin tosylate)". California Medicine. 98 (6): 318–9. PMC 1575756. PMID 13966844.
- ^ McGrath JC (June 2013). "2-Aminoethylnitrate: Earlier investigation as a drug was missed by recent authors due to changes in nomenclature". British Journal of Pharmacology. 169 (4): 949–50. doi:10.1111/bph.12148. PMC 3687673. PMID 23711023.
- ^ Ehrenberger W (August 1960). "[On the effects of 2-aminoethylnitrate p-toluenesulfonate (Nilatil) on coronary circulation disorders]". Wiener Zeitschrift für Innere Medizin und Ihre Grenzgebiete. 41: 323–4. PMID 13725976.
- ^ Fremont RE (May 1967). "Clinical and cardiographic evaluation of a new nitrate, itramin tosylate". Current Therapeutic Research, Clinical and Experimental. 9 (5): 235–46. PMID 4963057.
- ^ Kinnard WJ, Vogin EE, Aceto MD, Buckley JP (July 1964). "The Coronary Vasodilatory Effects of 2-Aminoethlynitrate p-Toluenesulfonate". Angiology. 15 (7): 312–5. doi:10.1177/000331976401500703. PMID 14177999. S2CID 29870356.
- ^ Takenaka F, Umeda T (July 1976). "Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts". Archives Internationales de Pharmacodynamie et de Therapie. 222 (1): 45–54. PMID 10860.
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Vasodilators used in cardiac diseases (C01D)
- Nitroglycerin #
- Isosorbide dinitrate #
- Isosorbide mononitrate
- Itramin tosilate
- Linsidomine
- Molsidomine
- Nicorandil
- Pentaerythritol tetranitrate
- Propatylnitrate
- Tenitramine
- Trolnitrate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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