LY-255582

LY-255582

Names
Preferred IUPAC name 3-{(3R,4R)-1-[(3S)-3-Cyclohexyl-3-hydroxypropyl]-3,4-dimethylpiperidin-4-yl}phenol
Identifiers
CAS Number	119193-09-8
3D model (JSmol)	Interactive image
ChemSpider	8081850
PubChem CID	9906198
InChI InChI=1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 Key: LVVHEFJXPXAUDD-BULFRSBZSA-N InChI=1/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 Key: LVVHEFJXPXAUDD-BULFRSBZBD
SMILES C[C@H]1CN(CC[C@@]1(C)C2=CC(=CC=C2)O)CC[C@@H](C3CCCCC3)O
Properties
Chemical formula	C22H35NO2
Molar mass	345.527 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.^[1] It has also been shown to reduce food and water consumption in rats.^[2]

See also

• κ-Opioid receptor § Antagonists
• List of investigational antidepressants

References

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