Lenticular fasciculus

Lenticular fasciculus
The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicate suppression of the target, blue arrows indicate stimulation of target structure. (Lenticular fasciculus visible but not labeled, as red line from GPi to THA.)
Details
Identifiers
Latin	fasciculus lenticularis
NeuroNames	441
NeuroLex ID	nlx_66287
TA98	A14.1.08.664 A14.1.09.521
TA2	5752
FMA	61976
Anatomical terms of neuroanatomy [edit on Wikidata]

The lenticular fasciculus is a tract connecting the globus pallidus (internus) to the thalamus and is a part of the thalamic fasciculus. It is synonymous with field H₂ of Forel. The thalamic fasciculus (composed of both the lenticular fasciculus and ansa lenticularis) runs to the thalamus. Basically, it is part of a pathway that connects the globus pallidus and the thalamus.

Lesions in this area can result in dyskinesias such as chorea-like movements.

External links

https://web.archive.org/web/20070419222336/http://www.endotext.org/neuroendo/neuroendo3b/neuroendo3b_2.htm (see figure #12)
https://web.archive.org/web/20080504234454/http://isc.temple.edu/neuroanatomy/lab/atlas/mdbg/

Anatomy of the diencephalon of the human brain

Epithalamus

Surface	Pineal gland Habenula Habenular trigone Habenular commissure
Grey matter	Pretectal area Habenular nuclei Subcommissural organ

Thalamus

Surface	Stria medullaris of thalamus Thalamic reticular nucleus Taenia thalami
Grey matter/ nuclei	paired: AN Ventral VA/VL VP/VPM/VPL Lateral LD LP Pulvinar nuclei Metathalamus MG LG P cell M cell K cell midline: MD Intralaminar Centromedian Midline nuclear group Interthalamic adhesion
White matter	Mammillothalamic tract Pallidothalamic tracts Ansa lenticularis Lenticular fasciculus Thalamic fasciculus PCML Medial lemniscus Trigeminal lemniscus Spinothalamic tract Lateral lemniscus Dentatothalamic tract Acoustic radiation Optic radiation Subthalamic fasciculus Anterior trigeminothalamic tract Medullary laminae

Hypothalamus

Surface

Grey matter

Autonomic zones	Anterior (parasympathetic/heat loss) Posterior (sympathetic/heat conservation)
Endocrine	posterior pituitary: Paraventricular Magnocellular neurosecretory cell Parvocellular neurosecretory cell Supraoptic oxytocin/vasopressin other: Arcuate (dopamine/GHRH) Preoptic (GnRH) Suprachiasmatic (melatonin)
Emotion	Lateral Ventromedial Dorsomedial

White matter

afferent
efferent
- Mammillothalamic tract
- Dorsal longitudinal fasciculus

Pituitary

Posterior is diencephalon, but anterior is glandular

Subthalamus

Rostral basal ganglia of the human brain and associated structures

Basal ganglia

Grey matter

Striatum	Dorsal striatum Putamen Caudate nucleus Ventral striatum Nucleus accumbens Olfactory tubercle Globus pallidus GPe GPi
Other	Amygdala Claustrum

White matter

Centrum semiovale

Internal capsule

Corona radiata

Pallidothalamic tracts: Thalamic fasciculus
- Ansa lenticularis
- Lenticular fasciculus
Subthalamic fasciculus

Rhinencephalon

Grey matter	Anterior olfactory nucleus Anterior perforated substance Olfactory bulb
White matter	Olfactory tract Medial olfactory stria Lateral olfactory stria Olfactory trigone

Other basal forebrain

Grey matter	Substantia innominata Nucleus basalis Nucleus of diagonal band
White matter	Diagonal band of Broca Stria terminalis

Archicortex:
Hippocampal formation/
Hippocampus anatomy

Grey matter	Hippocampus proper CA1 CA2 CA3 CA4 Dentate gyrus Fascia dentata Subiculum
White matter	Alveus Fimbria Perforant path Schaffer collateral

Brain and spinal cord: neural tracts and fasciculi

Sensory

DCML

1°:	Pacinian corpuscle/Meissner's corpuscle → Posterior column (Gracile fasciculus/Cuneate fasciculus) → Gracile nucleus/Cuneate nucleus
2°:	→ sensory decussation/arcuate fibers (Posterior external arcuate fibers, Internal arcuate fibers) → Medial lemniscus/Trigeminal lemniscus → Thalamus (VPL, VPM)
3°:	→ Posterior limb of internal capsule → Postcentral gyrus

Anterolateral/
pain

Fast/lateral	1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior Spinothalamic tract → Spinal lemniscus → VPL of Thalamus) → 3° (Postcentral gyrus) → 4° (Posterior parietal cortex) 2° (Spinomesencephalic tract → Superior colliculus of Midbrain tectum)
Slow/medial	1° (Group C nerve fiber → Spinoreticular tract → Reticular formation) → 2° (MD of Thalamus) → 3° (Cingulate cortex)

Motor

Pyramidal

flexion: Primary motor cortex → Posterior limb of internal capsule → Decussation of pyramids → Corticospinal tract (Lateral, Anterior) → Neuromuscular junction

Extrapyramidal

flexion:	Primary motor cortex → Genu of internal capsule → Corticobulbar tract → Facial motor nucleus → Facial muscles
flexion:	Red nucleus → Rubrospinal tract
extension:	Vestibulocerebellum → Vestibular nuclei → Vestibulospinal tract
extension:	Vestibulocerebellum → Reticular formation → Reticulospinal tract
Midbrain tectum → Tectospinal tract → muscles of neck

Basal ganglia

direct:	1° (Motor cortex → Striatum) → 2° (GPi) → 3° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 4° (Thalamocortical radiations → Supplementary motor area) → 5° (Motor cortex)
indirect:	1° (Motor cortex → Striatum) → 2° (GPe) → 3° (Subthalamic fasciculus → Subthalamic nucleus) → 4° (Subthalamic fasciculus → GPi) → 5° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 6° (Thalamocortical radiations → Supplementary motor area) → 7° (Motor cortex)
nigrostriatal pathway:	Pars compacta → Striatum

Cerebellar

Afferent

Vestibular nuclei → Vestibulocerebellar tract → ICP → Cerebellum → Granule cell

Pontine nuclei → Pontocerebellar fibers → MCP → Deep cerebellar nuclei → Granule cell

Inferior olivary nucleus → Olivocerebellar tract → ICP → Hemisphere → Purkinje cell → Deep cerebellar nuclei

Efferent

Dentate nucleus in Lateral hemisphere/pontocerebellum → SCP → Dentatothalamic tract → Thalamus (VL) → Motor cortex

Interposed nucleus in Intermediate hemisphere/spinocerebellum → SCP → Reticular formation, or → Cerebellothalamic tract → Red nucleus → Thalamus (VL) → Motor cortex

Fastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nuclei

Bidirectional:
Spinocerebellar

Unconscious proprioception	lower limb → 1° (muscle spindles → DRG) → 2° (Posterior thoracic nucleus → Dorsal/posterior spinocerebellar tract → ICP → Cerebellar vermis) upper limb → 1° (muscle spindles → DRG) → 2° (Accessory cuneate nucleus → Cuneocerebellar tract → ICP → Anterior lobe of cerebellum)
Reflex arc	lower limb → 1° (Golgi tendon organ) → 2° (Ventral/anterior spinocerebellar tract→ SCP → Cerebellar vermis) upper limb → 1° (Golgi tendon organ) → 2° (Rostral spinocerebellar tract → ICP → Cerebellum)