| # | Date | Film | Gross (USD) | Openings in the top ten |
| 1 | January 6, 2019 | Aquaman | $1,978,768 | Creed II (#2), Mortal Engines (#5), Once Upon a Deadpool (#10) |
| 2 | January 13, 2019 | Dragon Ball Super: Broly | $6,452,094 | Second Act (#2), Belzebuth (#5), Charming (#9) |
| 3 | January 20, 2019 | Glass | $4,154,438 | A Dog's Way Home (#3), The Upside (#8), BlacKkKlansman (#10) |
| 4 | January 27, 2019 | Mirreyes contra Godínez | $3,439,068 | How to Train Your Dragon: The Hidden World (#3), The Mule (#4), The Mermaid (#6) |
| 5 | February 3, 2019 | How to Train Your Dragon: The Hidden World | $6,194,441 | The Favourite (#6), Vice (#7), Pyewacket (#10) |
| 6 | February 10, 2019 | $3,316,563 | Escape Room (#3), Alita: Battle Angel 3D (#4), Green Book (#5), Final Score (#7) |
| 7 | February 17, 2019 | Alita: Battle Angel | $2,755,731 | My Best Friend's Wedding (#2), The Lego Movie 2: The Second Part (#4) |
| 8 | February 24, 2019 | Cold Pursuit | $1,405,081 | #LadyRancho (#4), The Prodigy (#7), Mia and the White Lion (#9) |
| 9 | March 3, 2019 | Happy Death Day 2U | $1,155,801 | Serenity (#7) |
| 10 | March 10, 2019 | Captain Marvel | $12,812,530 | Beautiful Boy (#8) |
| 11 | March 17, 2019 | $6,407,025 | En Las Buenas y las Malas (#2), Como Novio de Pueblo (#3), The Hole in the Ground (#4), Manou the Swift (#5), The Professor and the Madman (#7), The Lullaby (#9) |
| 12 | March 24, 2019 | $2,825,710 | The Quake (#2), Five Feet Apart (#3), Fighting with My Family (#6), Las Niñas Bien (#7), Ben Is Back (#8) |
| 13 | March 31, 2019 | Dumbo | $7,613,793 | Heilstätten (#5), Mary Queen of Scots (#7) |
| 14 | April 7, 2019 | Shazam! | $5,851,449 | Pet Sematary (#3), On the Basis of Sex (#8), The Extraordinary Journey of the Fakir (#9) |
| 15 | April 14, 2019 | No Manches Frida 2 | $4,649,576 | Wonder Park (#4), After (#6), Hellboy (#7), The Kid Who Would Be King (#8), Amoureux de Ma Femme (#10) |
| 16 | April 21, 2019 | The Curse of La Llorona | $3,765,912 | El Complot Mongol (#6), Breakthrough (#7) |
| 17 | April 28, 2019 | Avengers: Endgame | $31,905,293 | The Old Man & the Gun (#9) |
| 18 | May 5, 2019 | $10,688,838 | Us (#2), Long Shot (#4), Air Strike (#6), Spy Cat (#8) |
| 19 | May 12, 2019 | $4,297,244 | Pokémon Detective Pikachu (#2), Dulce Familia (#3), What They Had (#8), He's Out There (#10) |
| 20 | May 19, 2019 | Pokémon Detective Pikachu | $2,253,545 | John Wick: Chapter 3 – Parabellum (#3), A Dog's Journey (#4), Brightburn (#6), UglyDolls (#7), The Aftermath (#9) |
| 21 | May 26, 2019 | Aladdin | $8,913,265 | Just a Breath Away (#9), The Sun Is Also a Star (#10) |
| 22 | June 2, 2019 | $6,102,831 | Godzilla: King of the Monsters (#2), Rocketman (#4), Ma (#5) |
| 23 | June 9, 2019 | Dark Phoenix | $4,777,000 | Solteras (#4), The Queen's Corgi (#5) |
| 24 | June 16, 2019 | Men in Black: International | $3,924,232 | Greta (#6), Deadly Still (#10) |
| 25 | June 23, 2019 | Toy Story 4 | $23,812,010 | Hotel Mumbai (#6), I Still See You (#10) |
| 26 | June 30, 2019 | $12,731,416 | Annabelle Comes Home (#2), The Hustle (#3), Chicuarotes (#6) |
| 27 | July 7, 2019 | Spider-Man: Far From Home | $10,386,486 | Pain and Glory (#6) |
| 28 | July 14, 2019 | $5,147,280 | Child's Play (#3), Poms (#6), The Adventures of Jurassic Pet (#7) |
| 29 | July 21, 2019 | The Lion King | $18,415,933 | El Cuento de las Comadrejas (#9) |
| 30 | July 28, 2019 | $8,215,092 | Extremely Wicked, Shockingly Evil and Vile (#2), ¿Conoces a Tomás? (#5), The Golem (#8), Stuber (#9) |
| 31 | August 4, 2019 | Hobbs & Shaw | $6,470,918 | PAW Patrol: Mighty Pups! (#5), La Camarista (#8), Pulp Fiction: 25th Anniversary (#9) |
| 32 | August 11, 2019 | The Secret Life of Pets 2 | $4,955,982 | Crawl (#4), Bring the Soul: The Movie (#5), Redcon-1 (#7) |
| 33 | August 18, 2019 | Scary Stories to Tell in the Dark | $2,885,938 | Mentada de Padre (#4), Playmobil: The Movie (#7), Booksmart (#9), L'homme fidèle (#10) |
| 34 | August 25, 2019 | Once Upon a Time in Hollywood | $2,365,092 | The Art of Racing in the Rain (#4), Locos por la Herencia (#10) |
| 35 | September 1, 2019 | Angel Has Fallen | $1,635,982 | Yesterday (#3), Como Si Fuera la Primera Vez (#6) |
| 36 | September 8, 2019 | It Chapter Two | $9,145,982 | The Angry Birds Movie 2 (#2), Sonora (#10) |
| 37 | September 15, 2019 | $3,265,857 | Dora and the Lost City of Gold (#2), Mamá Se Fue de Viaje (#3), Kursk (#5), Red Joan (#8), Otryv (#9) |
| 38 | September 22, 2019 | Tod@s Caen | $2,495,642 | Ad Astra (#4), Rambo: Last Blood (#5), Midsommar (#8), Overcomer (#10) |
| 39 | September 29, 2019 | Abominable | $2,025,310 | Ready or Not (#6), Todas las Pecas del Mundo (#8), Anna (#9) |
| 40 | October 6, 2019 | Joker | $13,485,934 | 108 Costuras (#5), Nothing to Lose 2 (#7), Where'd You Go, Bernadette (#10) |
| 41 | October 13, 2019 | $8,395,942 | Gemini Man (#2), La Boda de la Abuela (#4), Good Boys (#5), After the Wedding (#6), Mercy Black (#8) |
| 42 | October 20, 2019 | Maleficent: Mistress of Evil | $7,625,831 | 47 Meters Down: Uncaged (#5), Late Night (#7) |
| 43 | October 27, 2019 | $4,166,098 | The Addams Family (#2), Zombieland: Double Tap (#4), Hustlers (#5), Un Papá Pirata (#7), Unplanned (#8) |
| 44 | November 3, 2019 | Terminator: Dark Fate | $2,625,885 | Día de Muertos (#4), Los Rodríguez y el Más Allá (#8), Downton Abbey (#9) |
| 45 | November 10, 2019 | Maleficent: Mistress of Evil | $1,700,753 | Doctor Sleep (#2), Playing with Fire (#4), Polvo (#8) |
| 46 | November 17, 2019 | $1,204,122 | Ford v Ferrari (#2), Placa de Acero (#8) |
| 47 | November 24, 2019 | Frozen II | $8,629,125 | |
| 48 | December 1, 2019 | $5,098,736 | Guadalupe Reyes (#2), Mary (#5), Killerman (#6), A Rainy Day in New York (#7) |
| 49 | December 8, 2019 | $2,815,849 | Last Christmas (#2), Knives Out (#3), 21 Bridges (#5), Cats and Peachtopia (#8) |
| 50 | December 15, 2019 | Jumanji: The Next Level | $4,526,878 | Official Secrets (#8) |
| 51 | December 22, 2019 | Star Wars: The Rise of Skywalker | $7,252,312 | Doblemente Embarazada (#4), The Good Liar (#5), Black Christmas (#7) |
| 52 | December 29, 2019 | $2,194,082 | Spies in Disguise (#3), El Hubiera Sí Existe (#4), Cats (#6), Parasite (#7), Jexi (#10) |
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