| # | Date | Film | Gross in euros | Gross in US dollars | Notes |
| 1 | January 6, 2019 | Aquaman | €1,159,591 | $1,321,471 | It was the weekend of Aquaman at the top-spot. |
| 2 | January 13, 2019 | €1,004,391 | $1,151,957 | |
| 3 | January 20, 2019 | Glass | €1,716,824 | $2,066,736 | |
| 4 | January 27, 2019 | Creed II | €1,873,683 | $2,137,444 | |
| 5 | February 3, 2019 | Under the Same Roof (Bajo el mismo techo) | €1,122,157 | $1,283,500 | Under the Same Roof was the first Spanish film to reach the number-one spot in 2019. It was also the worst number-one release of the year. |
| 6 | February 10, 2019 | Green Book | €983,135 | $1,105,599 | Green Book took the first place on its second week. |
| 7 | February 17, 2019 | Alita: Battle Angel | €1,729,453 | $1,987,242 | |
| 8 | February 24, 2019 | How to Train Your Dragon: The Hidden World | €2,471,230 | $2,644,332 | |
| 9 | March 3, 2019 | €1,587,586 | $1,804,485 | |
| 10 | March 10, 2019 | Captain Marvel | €4,134,129 | $4,894,726 | |
| 11 | March 17, 2019 | €2,032,700 | $2,450,009 | |
| 12 | March 24, 2019 | Pain and Glory (Dolor y gloria) | €1,236,130 | $1,407,446 | Pain and Glory was the second Spanish film to reach the number-one spot in 2019. |
| 13 | March 31, 2019 | Dumbo | €3,466,145 | $3,721,948 | |
| 14 | April 7, 2019 | €2,814,754 | $3,055,209 | |
| 15 | April 14, 2019 | I Can Quit Whenever I Want (Lo dejo cuando quiera) | €1,581,450 | $1,786,949 | I Can Quit Whenever I Want was the third Spanish film to reach the number-one spot in 2019. |
| 16 | April 21, 2019 | €2,014,252 | $2,194,708 | |
| 17 | April 28, 2019 | Avengers: Endgame | €10,337,265 | $13,440,594 | Avengers: Endgame had the best number-one and release of 2019. |
| 18 | May 5, 2019 | €3,625,237 | $4,119,574 | |
| 19 | May 12, 2019 | Detective Pikachu | €1,940,795 | $2,180,179 | |
| 20 | May 19, 2019 | €1,149,967 | $1,283,159 | |
| 21 | May 26, 2019 | Aladdin | €4,751,359 | $4,908,445 | |
| 22 | June 2, 2019 | €2,930,683 | $3,031,402 | |
| 23 | June 9, 2019 | €2,487,676 | $2,477,327 | |
| 24 | June 16, 2019 | €1,575,589 | $1,588,947 | |
| 25 | June 23, 2019 | Toy Story 4 | €3,097,234 | $3,681,484 | |
| 26 | June 30, 2019 | €2,439,609 | $2,638,967 | |
| 27 | July 7, 2019 | Spider-Man: Far From Home | €3,998,099 | $4,361,687 | |
| 28 | July 14, 2019 | €1,642,846 | $1,847,603 | |
| 29 | July 21, 2019 | The Lion King | €6,369,251 | $8,561,381 | |
| 30 | July 28, 2019 | €4,543,228 | $5,342,605 | |
| 31 | August 4, 2019 | €2,225,076 | $2,491,685 | |
| 32 | August 11, 2019 | The Secret Life of Pets 2 | €2,382,800 | $2,549,805 | |
| 33 | August 18, 2019 | Once Upon a Time in Hollywood | €2,220,974 | $2,412,140 | |
| 34 | August 25, 2019 | €1,236,056 | $1,370,250 | |
| 35 | September 1, 2019 | €860,100 | $939,670 | The third weekend of Once Upon a Time in Hollywood had the lowest number-one of 2019. |
| 36 | September 8, 2019 | It Chapter Two | €2,663,596 | $2,937,682 | |
| 37 | September 15, 2019 | €1,449,629 | $1,605,348 | |
| 38 | September 22, 2019 | Ad Astra | €1,908,705 | $2,103,024 | |
| 39 | September 29, 2019 | While at War (Mientras dure la guerra) | €1,208,428 | $1,331,454 | While at War was the fourth Spanish film to reach the number-one spot in 2019. |
| 40 | October 6, 2019 | Joker | €4,461,390 | $4,897,782 | |
| 41 | October 13, 2019 | €4,484,575 | $4,952,048 | |
| 42 | October 20, 2019 | €3,117,479 | ~$3,400,000 | |
| 43 | October 27, 2019 | €2,142,037 | ~$2,300,000 | |
| 44 | November 3, 2019 | €2,356,197 | $2,630,859 | |
| 45 | November 10, 2019 | €1,186,522 | $1,307,318 | |
| 46 | November 17, 2019 | If I Were Rich (Si yo fuera rico) | €2,110,242 | $2,332,017 | If I Were Rich was the fifth Spanish film to reach the number-one spot in 2019. |
| 47 | November 24, 2019 | Frozen II | €5,335,466 | $5,895,852 | |
| 48 | December 1, 2019 | €3,104,489 | $3,448,018 | |
| 49 | December 8, 2019 | €2,829,273 | $2,962,120 | |
| 50 | December 15, 2019 | Jumanji: The Next Level | €2,439,504 | $2,709,200 | |
| 51 | December 22, 2019 | Star Wars: The Rise of Skywalker | €5,442,764 | $7,742,726 | |
| 52 | December 29, 2019 | €2,880,477 | $3,250,818 | |
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