Lithium citrate
Chemical used in psychiatric treatment
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| Other names Trilithium citrate trilithium 2-hydroxypropane-1,2,3-tricarboxylate | |
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| ECHA InfoCard | 100.011.860  |
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| Properties | |
Chemical formula | Li3C6H5O7 |
| Molar mass | 209.923 g mol−1 |
| Appearance | Odorless white powder |
| Melting point | decomposes at 105 °C (221 °F; 378 K) |
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Hazard statements | H302, H319 |
Precautionary statements | P305+P351+P338 |
| Flash point | N/A |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).  N verify (what is  Y N ?) Infobox references | |
Chemical compound
Lithium citrate (Li3C6H5O7) is a lithium salt of citric acid that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.[1][2][3][4] There is extensive pharmacology of lithium, the active component of this salt.
Lithia water contains various lithium salts, including the citrate.
History
An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948[5] after it was banned by the Food and Drug Administration.[6]
Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder.[7] It can be administered orally in the form of a syrup.[7]
References
- ^ Medication description
- ^ "pms-Lithium Citrate - Uses, Side Effects, Interactions - MedBroadcast.com". medbroadcast.com. Retrieved 2017-08-15.
- ^ "Medical use". Archived from the original on 2006-06-15. Retrieved 2006-07-29.
- ^ "Lithium: medicine to control mood disorders such as mania and bipolar disorder". nhs.uk. 2020-08-17. Retrieved 2022-08-25.
- ^ Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.
- ^ "Here's the Gross Thing That Happens when You Mix 7-Up with Lithium". 20 February 2016.
- ^ a b PubChem. "Lithium citrate". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-09-08.
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- Ketamine
- Lithium (lithium acetate, lithium carbonate, lithium chloride, lithium citrate, lithium hydroxide, lithium orotate)
- Omega-3 fatty acids (docosahexaenoic acid, eicosapentaenoic acid)
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