MAP3K19

Protein-coding gene in the species Homo sapiens
MAP3K19
Identifiers
AliasesMAP3K19, RCK, YSK4, mitogen-activated protein kinase kinase kinase 19
External IDsMGI: 1203481; HomoloGene: 19318; GeneCards: MAP3K19; OMA:MAP3K19 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for MAP3K19
Genomic location for MAP3K19
Band2q21.3Start134,964,485 bp[1]
End135,047,468 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for MAP3K19
Genomic location for MAP3K19
Band1|1 E3Start127,742,528 bp[2]
End127,782,768 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • bronchial epithelial cell

  • right uterine tube

  • sperm

  • gonad

  • olfactory zone of nasal mucosa

  • mucosa of paranasal sinus

  • testicle

  • epithelium of nasopharynx

  • right testis

  • left testis
Top expressed in
  • fourth ventricle

  • choroid plexus of fourth ventricle

  • choroidal fissure

  • hypothalamus

  • floor plate

  • dentate gyrus of hippocampal formation granule cell

  • ovary

  • hippocampus proper

  • Cortex of frontal lobe

  • primary visual cortex
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • transferase activity
  • nucleotide binding
  • protein kinase activity
  • ATP binding
  • kinase activity
  • protein serine/threonine kinase activity
Cellular component
  • cytoplasm
Biological process
  • protein phosphorylation
  • phosphorylation
  • regulation of mitotic cell cycle
  • signal transduction
  • stress-activated protein kinase signaling cascade
  • activation of protein kinase activity
  • regulation of apoptotic process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

80122

22625

Ensembl

ENSG00000176601

ENSMUSG00000051590

UniProt

Q56UN5

E9Q3S4

RefSeq (mRNA)
NM_001018044
NM_001018045
NM_001018046
NM_001018047
NM_001282883

NM_025052
NM_001321177
NM_001018043
NM_001400438

NM_011737

RefSeq (protein)
NP_001018054
NP_001018056
NP_001018057
NP_001269812
NP_001308106

NP_079328

NP_035867

Location (UCSC)Chr 2: 134.96 – 135.05 MbChr 1: 127.74 – 127.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitogen-activated protein kinase kinase kinase 19 is a protein that in humans is encoded by the MAP3K19 gene. [5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176601 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051590 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Mitogen-activated protein kinase kinase kinase 19". Retrieved 2017-12-13.

Sources


  • v
  • t
  • e