Protein
| Melatonin receptor 1C |
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| Identifiers |
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| Symbol | Mtnr1c |
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| NCBI gene | 30661 |
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| RefSeq | AY166825 |
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| UniProt | Q804I9 |
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| Search for |
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| Structures | Swiss-model |
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| Domains | InterPro |
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Melatonin receptor 1C, also known as MTNR1C, is a protein that is encoded by the Mtnr1c gene. This receptor has been identified in fish, amphibia, and birds, but not in humans.[1]
References
- ^ Sugden D, Davidson K, Hough KA, Teh MT (2004). "Melatonin, melatonin receptors and melanophores: a moving story". Pigment Cell Res. 17 (5): 454–60. doi:10.1111/j.1600-0749.2004.00185.x. PMID 15357831.
Further reading
- Brzezinski A; Brzezinski, Amnon (1997). "Melatonin in humans". N. Engl. J. Med. 336 (3): 186–95. doi:10.1056/NEJM199701163360306. PMID 8988899.
- Reppert SM, Weaver DR, Ebisawa T, et al. (1996). "Cloning of a melatonin-related receptor from human pituitary". FEBS Lett. 386 (2–3): 219–24. doi:10.1016/0014-5793(96)00437-1. PMID 8647286. S2CID 38587331.
- Niles LP, Wang J, Shen L, et al. (2000). "Melatonin receptor mRNA expression in human granulosa cells". Mol. Cell. Endocrinol. 156 (1–2): 107–10. doi:10.1016/S0303-7207(99)00135-5. PMID 10612428. S2CID 42730113.
- Roy D, Angelini NL, Fujieda H, et al. (2001). "Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin". Endocrinology. 142 (11): 4711–20. doi:10.1210/en.142.11.4711. PMID 11606436.
- Ayoub MA, Couturier C, Lucas-Meunier E, et al. (2002). "Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer". J. Biol. Chem. 277 (24): 21522–8. doi:10.1074/jbc.M200729200. PMID 11940583.
- Yuan L, Collins AR, Dai J, et al. (2003). "MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells". Mol. Cell. Endocrinol. 192 (1–2): 147–56. doi:10.1016/S0303-7207(02)00029-1. PMID 12088876. S2CID 54393974.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Slominski A, Pisarchik A, Zbytek B, et al. (2003). "Functional activity of serotoninergic and melatoninergic systems expressed in the skin". J. Cell. Physiol. 196 (1): 144–53. doi:10.1002/jcp.10287. PMID 12767050. S2CID 24534729.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Suzuki S, Masui Y, Ohnuki M, et al. (2007). "Induction of metallothionein synthesis by cilostazol in mice and in human cultured neuronal cell lines". Biol. Pharm. Bull. 30 (4): 791–4. doi:10.1248/bpb.30.791. PMID 17409522.
See also
Cell surface receptor: G protein-coupled receptors
Class A: Rhodopsin-like |
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| Neurotransmitter | |
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Metabolites and
signaling molecules | |
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| Peptide | |
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| Miscellaneous | |
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| MT1Tooltip Melatonin receptor 1 | |
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| MT2Tooltip Melatonin receptor 2 | |
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| Unsorted | - Agonists: 2-Phenylmelatonin
- 5-Methoxyluzindole
- 6-Chloromelatonin
- 6-Fluoromelatonin
- 6-Methoxymelatonin
- 6,7-Dichloro-2-methylmelatonin
- 8-M-PDOT
- AMMTC
- GR-135,531 (of MT3Tooltip melatonin receptor 1C)
- N-Acetyltryptamine
- N-Butanoylmelatonin
- N-Propionylmelatonin
- S-24268
- S-25150
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- See also: Receptor/signaling modulators
- Adrenergics
- Dopaminergics
- Serotonergics
- Monoamine metabolism modulators
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Further reading
- Classification of protein families - Melatonin receptor type 1C
- Sleep drops with melatonin and lavender in German
- Melatonin receptor genes (mel-1a, mel-1b, mel-1c) are differentially expressed in the avian germ line
