Methimepip

Methimepip
Names
IUPAC name
4-(1H-imidazol-4-ylmethyl)-1-methylpiperidine
Identifiers
CAS Number
  • 151070-80-3 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL175782 ☒N
ChemSpider
  • 9488804 ☒N
IUPHAR/BPS
  • 1254
MeSH C500075
PubChem CID
  • 11313837
UNII
  • 259YSH2WL6 checkY
CompTox Dashboard (EPA)
  • DTXSID80462102 Edit this at Wikidata
InChI
  • InChI=1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) ☒N
    Key: KIAVPENCSGKVQP-UHFFFAOYSA-N ☒N
  • InChI=1/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
    Key: KIAVPENCSGKVQP-UHFFFAOYAQ
  • CN1CCC(CC1)CC2=CN=CN2
Properties
Chemical formula
C10H17N3
Molar mass 179.262 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references
Chemical compound

Methimepip is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.[1]

References

  1. ^ Kitbunnadaj R, Hashimoto T, Poli E, et al. (March 2005). "N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist". Journal of Medicinal Chemistry. 48 (6): 2100–7. doi:10.1021/jm049475h. PMID 15771452.
  • v
  • t
  • e
Histamine receptor modulators
H1
Agonists
Antagonists
  • Unknown/unsorted: Azanator
  • Belarizine
  • Elbanizine
  • Flotrenizine
  • GSK1004723
  • Napactadine
  • Tagorizine
  • Trelnarizine
  • Trenizine
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors


Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e