Midget cell

Midget cell
A sketch of a parasol cell (right) alongside a midget cell (left) for size comparison
Details
Part ofRetina of eye
SystemVisual system
Identifiers
FMA62360
Anatomical terminology
[edit on Wikidata]

A midget cell is one type of retinal ganglion cell (RGC). Midget cells originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). The axons of midget cells travel through the optic nerve and optic tract, ultimately synapsing with parvocellular cells in the LGN. These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies. About 80% of RGCs are midget cells. They receive inputs from relatively few rods and cones. In many cases, they are connected to midget bipolar cells, which are linked to one cone each.[1]

These neurons show roughly circular receptive fields with antagonistic center and surround; this property is known as spatial opponency and these neurons are typically divided into ON- or OFF-center, depending on whether they are excited or inhibited by photons falling on the center of their receptive fields.[2] Most of these cells are chromatically opponent, meaning that long- and medium-wavelength visible light (commonly approximated to red and green, respectively) exert opposing effects on the center and the surround.[2] For instance, a chromatically opponent L-ON midget cell would be excited (and more likely to spike action potentials) if light of long wavelength falls on the cone or cones in the center of its receptive field but would be inhibited by medium-wavelength light falling on the surround of its receptive field.[2] However, not all midget cells are chromatically opponent.[2]

They have slow conduction velocity and are very responsive to high temporal frequencies (i.e. rapidly and low spatial frequencies).[3]

See also

References

  1. ^ "Eye, human."Encyclopædia Britannica. 2008. Encyclopædia Britannica 2006 Ultimate Reference Suite DVD
  2. ^ a b c d Le, Wool; Jd, Crook; Jb, Troy; Os, Packer; Q, Zaidi; Dm, Dacey (2018-02-07). "Nonselective Wiring Accounts for Red-Green Opponency in Midget Ganglion Cells of the Primate Retina". The Journal of Neuroscience. 38 (6): 1520–1540. doi:10.1523/JNEUROSCI.1688-17.2017. PMC 5815352. PMID 29305531.
  3. ^ Kandel, Eric; Schwartz, James; Jessell, Thomas (2000-01-05). Principles of Neural Science, Fourth Edition. ISBN 0838577016.

External links

  • Media related to Midget cell at Wikimedia Commons
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1:posterior segment 2:ora serrata 3:ciliary muscle 4:ciliary zonules 5:Schlemm's canal 6:pupil 7:anterior chamber 8:cornea 9:iris 10:lens cortex 11:lens nucleus 12:ciliary process 13:conjunctiva 14:inferior oblique muscule 15:inferior rectus muscule 16:medial rectus muscle 17:retinal arteries and veins 18:optic disc 19:dura mater 20:central retinal artery 21:central retinal vein 22:optic nerve 23:vorticose vein 24:bulbar sheath 25:macula 26:fovea 27:sclera 28:choroid 29:superior rectus muscle 30:retina1: posterior segment2: ora serrata3: ciliary muscle4: ciliary zonules5: Schlemm's canal6: pupil7: anterior chamber8: cornea9: iris10: lens cortex11: lens nucleus12: ciliary process13: conjunctiva14: inferior oblique muscule15: inferior rectus muscule16: medial rectus muscle17: retinal arteries and veins18: optic disc19: dura mater20: central retinal artery21: central retinal vein22: optic nerve23: vorticose vein24: bulbar sheath25: macula26: fovea27: sclera28: choroid29: superior rectus muscle30: retina
1:posterior segment 2:ora serrata 3:ciliary muscle 4:ciliary zonules 5:Schlemm's canal 6:pupil 7:anterior chamber 8:cornea 9:iris 10:lens cortex 11:lens nucleus 12:ciliary process 13:conjunctiva 14:inferior oblique muscule 15:inferior rectus muscule 16:medial rectus muscle 17:retinal arteries and veins 18:optic disc 19:dura mater 20:central retinal artery 21:central retinal vein 22:optic nerve 23:vorticose vein 24:bulbar sheath 25:macula 26:fovea 27:sclera 28:choroid 29:superior rectus muscle 30:retina
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