Monoamine receptor

A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine structure. The monoamine receptors are almost all G protein-coupled receptors, with the serotonin 5-HT₃ receptor being a notable exception as a ligand-gated ion channel.^[1] Monoamine receptors are the biological targets of many drugs; such drugs may be referred to as "monoaminergic".

List of receptors

Monoamine receptors include the following classes:

• Adrenergic receptors – bound by epinephrine (adrenaline) and norepinephrine (noradrenaline)
• Dopamine receptors – bound by dopamine
• Histamine receptors – bound by histamine
• Melatonin receptors – bound by melatonin
• Serotonin receptors – bound by serotonin (5-HT)
• Trace amine-associated receptors – bound by trace amines, thyronamines, monoamine neurotransmitters (TAAR1 only), and trimethylamine (TAAR5 only)

References

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