Neuropeptide FF receptor 1

Protein-coding gene in the species Homo sapiens
NPFFR1
Identifiers
AliasesNPFFR1, GPR147, NPFF1, NPFF1R1, OT7T022, neuropeptide FF receptor 1
External IDsOMIM: 607448 MGI: 2685082 HomoloGene: 23348 GeneCards: NPFFR1
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for NPFFR1
Genomic location for NPFFR1
Band10q22.1Start70,247,329 bp[1]
End70,284,004 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for NPFFR1
Genomic location for NPFFR1
Band10|10 B4Start61,431,271 bp[2]
End61,464,344 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • cerebellar cortex

  • cerebellar hemisphere

  • spinal cord

  • nucleus accumbens

  • occipital lobe

  • hypothalamus

  • tibial nerve

  • superior frontal gyrus

  • mesencephalon

  • substantia nigra
Top expressed in
  • hypothalamus

  • hippocampus proper

  • superior frontal gyrus

  • cerebellar cortex

  • mesencephalon

  • olfactory bulb

  • spermatid

  • white adipose tissue

  • spermatocyte

  • esophagus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • peptide binding
  • signal transducer activity
  • G protein-coupled receptor activity
  • neuropeptide receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • integral component of plasma membrane
  • membrane
  • cilium
Biological process
  • cellular response to hormone stimulus
  • signal transduction
  • response to peptide
  • neuropeptide signaling pathway
  • G protein-coupled receptor signaling pathway
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

64106

237362

Ensembl

ENSG00000148734

ENSMUSG00000020090

UniProt

Q9GZQ6

E9Q468

RefSeq (mRNA)

NM_022146

NM_001177511

RefSeq (protein)

NP_071429

NP_001170982

Location (UCSC)Chr 10: 70.25 – 70.28 MbChr 10: 61.43 – 61.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuropeptide FF receptor 1, also known as NPFF1 is a human protein, encoded by the NPFFR1 gene.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148734 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020090 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: NPFFR1 neuropeptide FF receptor 1".

Further reading

  • Bonini JA, Jones KA, Adham N, et al. (2001). "Identification and characterization of two G protein-coupled receptors for neuropeptide FF". J. Biol. Chem. 275 (50): 39324–31. doi:10.1074/jbc.M004385200. PMID 11024015.
  • Hinuma S, Shintani Y, Fukusumi S, et al. (2000). "New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals". Nat. Cell Biol. 2 (10): 703–8. doi:10.1038/35036326. PMID 11025660. S2CID 2580390.

External links

  • "Neuropeptide FF Receptors: NPFF1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-09.
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Neurotransmitter
Adrenergic
Purinergic
Serotonin
Other
Metabolites and
signaling molecules
Eicosanoid
Other
Peptide
Neuropeptide
Other
Miscellaneous
Taste, bitter
Orphan
Other
Adhesion
Orphan
Other
Taste, sweet
Other
Class F: Frizzled & Smoothened
Frizzled
Smoothened