Neurotransmitter | Type | Location[1] | Function[1] |
ATP | non-peptide | postganglionic sympathetic neurons (e.g. in blood vessels & vas deferens) | Fast depolarization/contraction (vasoconstriction) |
GABA | non-peptide | ENSs | peristalsis |
5-HT | non-peptide | ENSs | peristalsis |
dopamine | non-peptide | some SNSs (e.g. kidney) | vasodilation |
NO | non-peptide | gastric nerves & Pelvic Nerve | |
NPY | peptide | postganglionic sympathetic neurons (e.g. blood vessels) | - enhance vasoconstrictor action of noradrenaline
- noradrenaline release inhibitor
|
VIP | peptide | - parasympathetic nerves to salivary glands
- NANC innervation to smooth muscle of airways
- parasympathetic ganglia in sphincters, gallbladder and small intestine
| |
GnRH | peptide | sympathetic ganglia | - slow depolarization
- acetylcholine cotransmitter
|
substance P | peptide | | - slow depolarization
- acetylcholine cotransmitter
|
CGRP | peptide | non-myelinated sensory neurons | |