Protein-coding gene in the species Homo sapiens
OR2J1 |
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Identifiers |
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Aliases | OR2J1, 6M1-4P, OR2J1P, OR6-15, OR6-5, dJ80I19.2, hs6M1-4, olfactory receptor family 2 subfamily J member 1 (gene/pseudogene), olfactory receptor family 2 subfamily J member 1 |
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External IDs | GeneCards: OR2J1 |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6p22.1 | Start | 29,099,490 bp[1] |
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End | 29,102,701 bp[1] |
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Gene ontology |
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Molecular function | - G protein-coupled receptor activity
- olfactory receptor activity
- signal transducer activity
| Cellular component | - integral component of membrane
- plasma membrane
- membrane
| Biological process | - sensory perception of smell
- signal transduction
- response to stimulus
- detection of chemical stimulus involved in sensory perception of smell
- G protein-coupled receptor signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | ENSG00000204702 ENSG00000226931 ENSG00000225441 ENSG00000234305 ENSG00000235632
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ENSG00000226192 ENSG00000234804 ENSG00000206523 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 29.1 – 29.1 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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Olfactory receptor 2J1 is a protein that in humans is encoded by the OR2J1 gene.[3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]
See also
References
- ^ a b c ENSG00000226931, ENSG00000225441, ENSG00000234305, ENSG00000235632, ENSG00000226192, ENSG00000234804, ENSG00000206523 GRCh38: Ensembl release 89: ENSG00000204702, ENSG00000226931, ENSG00000225441, ENSG00000234305, ENSG00000235632, ENSG00000226192, ENSG00000234804, ENSG00000206523 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: OR2J1 olfactory receptor, family 2, subfamily J, member 1".
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
External links
- OR2J1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class I (fish-like receptors) | Family 51 | |
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Family 52 | |
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Family 56 | |
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Class II (tetrapod specific receptors) | Family 1 | |
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