ORG-20599

ORG-20599

Names
IUPAC name (2β,3α,5β)-21-chloro-3-hydroxy-2-morpholin-4-ylpregnan-20-one
Other names 2-chloro-1-[(2S,3S,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Identifiers
CAS Number	156685-94-8 Y
3D model (JSmol)	Interactive image
ChemSpider	8025739
PubChem CID	9850026
CompTox Dashboard (EPA)	DTXSID30349651
InChI InChI=1S/C25H40ClNO3/c1-24-8-7-19-17(18(24)5-6-20(24)23(29)15-26)4-3-16-13-22(28)21(14-25(16,19)2)27-9-11-30-12-10-27/h16-22,28H,3-15H2,1-2H3/t16-,17-,18-,19-,20+,21-,22-,24-,25-/m0/s1 Key: NZFNABGZEQPYBX-PMBZPZLSSA-N InChI=1/C25H40ClNO3/c1-24-8-7-19-17(18(24)5-6-20(24)23(29)15-26)4-3-16-13-22(28)21(14-25(16,19)2)27-9-11-30-12-10-27/h16-22,28H,3-15H2,1-2H3/t16-,17-,18-,19-,20+,21-,22-,24-,25-/m0/s1 Key: NZFNABGZEQPYBX-PMBZPZLSBZ
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)CCl)CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C
Properties
Chemical formula	C25H40ClNO3
Molar mass	438.04 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

ORG-20599 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABA_A receptor positive allosteric modulator and, at higher concentrations, agonist.^[1][2] It was developed for use as an anaesthetic agent but was never marketed for this purpose, although it is still used in scientific research.^[3][4]

Chemistry

References

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