PAK1IP1

Protein-coding gene in the species Homo sapiens
PAK1IP1
Identifiers
AliasesPAK1IP1, MAK11, PIP1, WDR84, bA421M1.5, hPIP1, PAK1 interacting protein 1
External IDsOMIM: 607811 MGI: 1915333 HomoloGene: 39574 GeneCards: PAK1IP1
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for PAK1IP1
Genomic location for PAK1IP1
Band6p24.2Start10,694,972 bp[1]
End10,709,782 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for PAK1IP1
Genomic location for PAK1IP1
Band13|13 A3.3Start41,154,499 bp[2]
End41,166,491 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • prostate

  • Achilles tendon

  • endometrium

  • islet of Langerhans

  • smooth muscle tissue

  • gastrocnemius muscle

  • monocyte

  • rectum

  • appendix

  • placenta
Top expressed in
  • otic placode

  • morula

  • maxillary prominence

  • saccule

  • medial ganglionic eminence

  • subcutaneous adipose tissue

  • epithelium of stomach

  • arcuate nucleus

  • hair follicle

  • seminal vesicula
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • nucleolus
  • nucleus
Biological process
  • roof of mouth development
  • negative regulation of signal transduction
  • cell population proliferation
  • ribosomal large subunit biogenesis
  • regulation of signal transduction by p53 class mediator
  • ribosome biogenesis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55003

68083

Ensembl

ENSG00000111845
ENSG00000285226

ENSMUSG00000038683

UniProt

Q9NWT1

Q9DCE5

RefSeq (mRNA)

NM_017906

NM_026550

RefSeq (protein)

NP_060376

NP_080826

Location (UCSC)Chr 6: 10.69 – 10.71 MbChr 13: 41.15 – 41.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

p21-activated protein kinase-interacting protein 1 is an enzyme that in humans is encoded by the PAK1IP1 gene.[5][6]


Interactions

PAK1IP1 has been shown to interact with PAK1.[5]

References

  1. ^ a b c ENSG00000285226 GRCh38: Ensembl release 89: ENSG00000111845, ENSG00000285226 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038683 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Xia C, Ma W, Stafford LJ, Marcus S, Xiong WC, Liu M (May 2001). "Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1". Proc Natl Acad Sci U S A. 98 (11): 6174–9. Bibcode:2001PNAS...98.6174X. doi:10.1073/pnas.101137298. PMC 33441. PMID 11371639.
  6. ^ "Entrez Gene: PAK1IP1 PAK1 interacting protein 1".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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