Para-Bromoamphetamine
Chemical compound
- none
- 1-(4-bromophenyl)propan-2-amine
- 18455-37-3 N
- 205668
- 178189 Y
- 6IBU62D1N2
- ChEMBL61355 Y
- DTXSID90896914
- Interactive image
- Brc1ccc(cc1)CC(N)C
InChI
- InChI=1S/C9H12BrN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3 Y
- Key:SMNXUMMCCOZPPN-UHFFFAOYSA-N Y
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.
Another related compound is para-bromomethamphetamine known by the codename V-111.[1]
Neurotoxicity
Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.[2]
See also
- Substituted amphetamines
- 4-Bromomethcathinone (4-BMC)
- 4-Fluoroamphetamine (4-FA)
- para-Chloroamphetamine (PCA)
- para-Iodoamphetamine (PIA)
References
- ^ Magyar K, Tekes K, Zólyomi G, Szüts T, Knoll J (1981). "The fate of p-bromo-methylamphetamine (V-111) in the body". Acta Physiologica Academiae Scientiarum Hungaricae. 57 (3): 285–307. PMID 7304194.
- ^ Fuller RW, Baker JC, Perry KW, Molloy BB (October 1975). "Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: drug levels in brain and effects on brain serotonin metabolism". Neuropharmacology. 14 (10): 739–46. doi:10.1016/0028-3908(75)90099-4. PMID 1196472. S2CID 9620299.
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See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine metabolism modulators
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